四君子汤治疗脾胃气虚证的疗效探究

Exploration on curative effect of Sijunzi decoction in the treatment of syndrome of qi deficiency of spleen and stomach

目的分析四君子汤治疗脾胃气虚证的疗效及安全性。方法 68例脾胃气虚证患者,随机分为对照组及观察组,各34例。对照组给予常规疗法,观察组在对照组基础上给予患者中药方剂四君子汤治疗。比较两组患者临床疗效。结果观察组总有效率94.12%高于对照组73.53%,差异具有统计学意义(χ2=5.314,P<0.05)。观察组疾病复发率(2.94%)低于对照组(17.65%),不良反应恶心呕吐、失眠烦躁发生率(2.94%、5.88%)低于对照组(17.65%、23.53%),差异均具有统计学意义(P<0.05)。结论中药四君子汤治疗脾胃气虚证,能够显著提高患者临床疗效,减少不良反应及复发率,对患者预后具有促进作用。

Objective To analyze the curative effect and safety of Sijunzi decoction in the treatment of syndrome of qi deficiency of spleen and stomach. Methods A total of 68 patients with qi deficiency of spleen and stomach were randomly divided into control group and observation group, with 34 cases in each group. The control group received conventional therapy, and the observation group received Chinese medicinal formulae of Sijunzi decoction for treatment. Clinical curative effect was compared in two groups. Results The observation group had higher total effective rate as 94.12% than 73.53% in the control group, and the difference had statistical significance（χ-2 =5.314, P〈0.05）. The observation group had lower disease recurrence rate（2.94%） than the control group（17.65%）, and lower incidence of nausea and vomiting and insomnia and restless（2.94% and 5.88%） than the control group（17.65% and 23.53%）. Their difference had statistical significance（P〈0.05）. Conclusion For the treatment of qi deficiency of spleen and stomach, Chinese medicinal formulae of Sijunzi decoction can significantly improve clinical curative effect, reduce occurrence of adverse reactions and recurrence rate, and it also has a promoting effect for prognosis.