子宫腺肌病患者高强度聚焦超声治疗后妊娠结局的观察

Observation on pregnancy outcomes after high intensity focused ultrasound ablation therapy in patients with adenomyosis

目的探讨高强度聚焦超声(HIFU)消融治疗子宫腺肌病(AM)后对患者妊娠结局的影响。方法选择2011年4月至2016年2月在重庆海扶医院接受HIFU消融并成功妊娠的AM患者20例,回顾性分析患者的妊娠及分娩情况。结果 HIFU治疗后患者痛经及经量增多症状较术前均明显改善(P<0.05)。20例AM患者HIFU术后平均受孕时间为(8.75±6.23)个月,其中11例成功分娩,5例自然流产,1例宫外孕,1例人工流产,2例仍处于妊娠期。所有患者在妊娠或分娩期无子宫破裂,新生儿均为健康儿。结论 HIFU消融是治疗AM的一种有效方式,能安全用于治疗有生育要求的AM患者。

Objective To investigate the influence of high intensity focused ultrasound（HIFU） ablation therapy on pregnancy outcomes in the patients with adenomyosis（AM）. Methods Twenty patients with AM and successful pregnancy after HIFU ablation in Chongqing Haifu Hospital from April 2011 to February 2016 were selected. Their pregnancy and delivery situation were retrospectively analyzed. Results After HIFU treatment, the symptoms of dymenorrhea and menorrhagia were significantly improved compared with before operation（P〈0.05）. The average fertilization time after HIFU was（8. 75 ±6.23） months, among them 11 cases succeeded in delivery,5 cases had spontaneous abortion, 1 case was ectopic pregnancy, 1 case took artificial abortion and 2 cases were still in pregnant period all cases had no uterime rupture during pregnant or delivery period. Neonateswere healthy. Conclusion HIFU ablation is an effective mode for treating AM and can be used in the patients with AM and birth demand.