多次献血者铁缺乏情况调查

Investigation of iron deficiency in multiple blood donors

目的研究全血和血小板献血者的铁营养状态,分析献血行为对献血者健康的影响。方法选取2015年6月至2016年7月初次自愿捐献全血400、200 ml和血小板1、2 U的献血者各30名,自愿捐献全血和单采血小板多次献血者各154名和128名,对研究对象献血前血液中血清铁(SI)、血清铁蛋白(SF)含量进行检测分析。结果全血献血者的初次组、多次组的组内、组间比较,SI、SF含量差异均无统计学意义(P>0.05)。血小板初次献血组SI、SF含量差异无统计学意义(P>0.05),随着采取血小板次数增多,其多次组间SI、SF含量差异有统计学意义(P<0.01)。结论多次捐献全血不会发生铁缺乏,多次单采血小板可能会发生铁缺乏,捐献血小板次数越多出现铁缺乏的几率越大。

Objective To investigate the iron status of blood donors, and analyze the influent of blood donation to donors＇ health. Methods From June, 2015 to July, 2016, 30 voluntary blood donors of first donation of whole blood 400 ml group and 200 ml group, platelet 1 unit group and 2 units group, and 154 voluntary blood donorsof more than one time donations of whole blood donation, and 128 of apheresis platelets donation were selected for the study. Serum iron and serum ferritin levels were measured before and after donation. Results There was no significant difference in the contents of SI and SF between the whole blood groups （P〉0.05）. There was no significant difference in the SI and SF contents of the first time platelet donation between the 2-unit group and the 1-unit group （P〉0.05）. Among the frequently donated platelets donors, the SI and SF contents of the 2-unit group and the 1-unit group appeared significant difference （P〈O.01）. Conclusion The occurrence of iron deficiency was not related to the numbers of donated whole blood, while it was related to frequent donation of platelets. The more times the donations of platelet, the greater probability of iron deficiency.