6303例腹泻儿童A群轮状病毒抗原检测结果

A study on 6303 cases of children diarrhea with A group rotavirus antigen test

目的分析广州地区腹泻儿童A群轮状病毒(RV)抗原检测结果,探讨该地区A群RV感染与患儿年龄、性别及感染季节的相关性。方法选取腹泻儿童6 303例,检测其A群RV抗原并行统计学分析。结果 6 303例腹泻患儿中,RV感染2 489例,阳性率为39.49%。1~岁患儿RV感染率最高,阳性率为48.30%(占43.87%);其次是0~岁患儿,阳性率为45.59%(占24.95%);2~岁患儿阳性率为45.02%(占9.80%)。男性患儿RV阳性率为39.13%,女性患儿RV阳性率为39.96,差异无统计学意义(P>0.05)。10、11、12、1月是RV感染的发病高峰期,占84.44%。结论 A群轮状病毒感染与儿童腹泻存在密切关系,婴幼儿是A群RV的易感人群,A群RV感染无性别差异且高发于秋冬季节。

Objective To explore the relationship between A group rotavirus infection and gender and age of patients and susceptible seasons in this region by studying A group rotavirus antigen test of children diarrhea in Guangzhou. Method 6 303 cases of children diarrhea were selected for the A group rotavirus antigen test. Results There were 2 489 cases of rotavirus infection in 6 303 cases of children diarrhea; the positive rate was 39.49%. The highest RV infection rate wasthe one year old age group （positive rate was 48.30%, 43.87% of total） , followed by zero year age group （positive rate was 45.59%, 24.95% of total） , and then the 2 years old age group （positive rate was 45.02%, 9.80% of total）. RV positive ratio in males was 39.13%, and in females was 39.96%. There was no significant differrence （P〉0.05）. Furthermore, the peak seasons of susceptibility to RV infection were October to next January, 84.44% of total. Conclusion There was a close connection between A group rotavirus infection and children diarrhea. Infants were susceptible population of A group rotavirus, A group rotavirus infection rates of male and female had no significant difference, and spring and autumn were the peak seasons of infection.