可疑青光眼48小时眼压变动规律的临床研究

48-hour intraocular pressure monitoring in glaucoma suspects

目的探讨可疑青光眼患者48 h眼压变动规律。方法选择临床上疑似青光眼患者180例(360只眼),进行48 h眼压测量。测量自入院时10AM开始至第3天清晨8AM,取偶数时间点,每2 h测量1次眼压。结果进入研究的360只眼中,130只眼(36.11%)的眼压昼夜波动小于8 mm Hg,230只眼(63.89%)出现昼夜波动过大。眼压高峰通常出现在2AM、4AM、6AM和8AM几个时间点,最少出现在6PM、8PM、10PM时间点。结论 48 h眼压的波动存在个体差异,对于可疑青光眼的临床诊断和治疗具有一定的参考价值。

Objective To determine the value of 48-hour intraocular pressure（ IOP） monitoring in routine clinical practice for the suspects of glaucoma. Methods 180 suspects of glaucoma（ 360 eyes） were selected for 48-hour IOP monitoring from 10 AM to 8AM on the third day（ once in 2 hours）. Results IOP variation amplitude was below 8 mm Hg in130 eyes（ 36. 11%） and higher than 8 mm Hg in 230 eyes（ 63. 89%）. Peak IOP occurred at 4AM,6AM and 8AM and was less commonly at 6PM,8PM or 10 PM. Conclusions 48-hour IOP measurement has individual variance. It is a good way to help us to diagnose and treat suspects of glaucoma.