鲜益母草胶囊联合缩宫素促进产后子宫复旧临床观察

Clinical Observation of Fresh Leonurus Japonicus Capsules Combined with Oxytocin for the Promotion of Uterine Involution after Delivery

目的:观察鲜益母草胶囊联合缩宫素促进产后子宫复旧的疗效。方法:选取在本院行剖宫产术的92例产妇,随机分为观察组与对照组,每组46例。2组均予抗生素预防产后感染,对照组在使用抗生素的基础上肌肉注射缩宫素,观察组在对照组用药基础上联合鲜益母草胶囊治疗。治疗后比较2组恶露、腹痛持续时间及子宫体积,评估临床疗效,检测白细胞计数(WBC)、红细胞计数(RBC)、血红蛋白(Hb)、血小板计数(BPC)及血浆黏稠度(PV)、纤维蛋白原(Fi B)、红细胞压积(HCT)、血沉(ESR)水平。结果:治疗后,2组恶露及腹痛持续时间均短于对照组,子宫体积小于对照组,差异均有统计学意义(P<0.05)。观察组总有效率为91.30%,高于对照组的73.91%,差异有统计学意义(P<0.05)。观察组RBC、Hb水平均高于对照组,差异均有统计学意义(P<0.05)。2组WBC及BPC水平比较,差异均无统计学意义(P>0.05)。观察组PV、Fi B水平均低于对照组,ESR水平高于对照组,差异均有统计学意义(P<0.05)。2组HCT水平比较,差异无统计学意义(P>0.05)。结论:鲜益母草胶囊联合缩宫素能有效改善产妇产后的血常规和血液流变学指标,加快子宫收缩,促进子宫复旧。

Objective：To observe the curative effect of fresh leonurus japonicus capsules combined with oxytocin in promoting uterine involution after delivery. Methods ： Selected 92 cases of parturient women who received cesarean section in our hospital,and divided them into the observation group and the control group randomly,46 cases in each group. Both groups received antibiotics for preventing puerperal infection. In addition,the control group was treated with intramuscular injection of oxytocin, and the observation group was treated with fresh leonurus japonicus capsules combined with oxytocin. After treatment,compared the duration of lochia and abdominal distension,as well as uterine volume,and evaluated clinical effect in both groups. Detected white blood cell count（WBC）,red blood cell count（RBC）,hemoglobin（Hb）,platelet count（BPC） and levels of plasma viscosity（PV）,fibrinogen（FiB）,hematocrit（HTC） and erythrocyte sedimentation rate（ESR） in both groups. Results ：After treatment,the duration of lochia and abdominal distension in the observation group was shorter than that in the control group,while the uterine volume in the observation group was smaller than that in the control group（P〈0.05）. The total effective rate was 91.30% in the observation group, being higher than 73.91% in the control group（P〈0.05）. Levels of RBC and Hb in the observation group were both higher than those in the control group. No significant difference was found in the comparison of levels of WBC and BPC between two groups（P〈0.05）. Levels of PV and FiB in the observation group were lower than those in the control group,while ESR levels in the observation group were higher than those in the control group（P〉0.05）. No significant difference was found in the comparison of HCT levels between two groups（P〉0.05）. Conclusion：The therapy of fresh leonurus japonicus capsules combined with oxytocin can effectively improve blood routine and hemorheology indexes of women after delivery. It can speed up uterine contraction and promote uterine involution.