儿童唾液腺上皮性肿瘤的诊断与治疗

Diagnosis and treatment of epithelial salivary gland tumors in children

目的探讨16岁以下儿童唾液腺上皮性肿瘤的临床病理类型、诊断及治疗方法。方法对在1983年至2013年间住院治疗的26例儿童唾液腺上皮性肿瘤的临床病理类型、诊断、治疗、预后进行分析及总结。结果 26例儿童唾液腺上皮性肿瘤中良性肿瘤19例(73.1%),以多形性腺瘤最为多见;恶性肿瘤7例(26.9%),以黏液表皮样癌最多见。肿瘤最常发生在腮腺,共14例,其次是腭部小唾液腺,6例。26例均经外科手术治疗,并获得3年以上的随访,良性肿瘤均无复发,恶性肿瘤一例复发。结论儿童唾液腺上皮性肿瘤以腮腺最为多发,其次为腭部小唾液腺。恶性肿瘤比例较成人高。治疗以手术切除为主,应重视术前组织学诊断,尽量避免术后复发及并发症的发生。

Objective To study the pathological classification, diagnosis and treatment on epithelial salivary gland tumors in children. Methods The pathological type, diagnosis, treatment and prognosis were analyzed in 26 cases of epithelial salivary gland tumors of children treated from 1983 to 2013 in our hospital. Results In the 26 cases of epithelial salivary gland tumors of children, 19 cases （73.1%） were benign tumor and most of them were pleomorphic adenoma; 7 cases （26.9%） were malignant tumor in which mucoepidermoid carcinoma were maximum. As most common site, 14 cases were occurred at parotid, followed by minor salivary gland in palate. All patients were treated with surgery and received 3-year or more follow-up examination after the surgery. No benign tumor recurred and only one case malignant tumor was recurred. Conclusion Surgery is the best therapy for epithelial salivary gland tumors of children. Histology diagnosis should be obtained before operation. It is important to avoid relapse after operation and prevent the occurrence of complication.