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靶向HER2药物治疗胃癌的研究 被引量:1

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摘要 胃癌属于消化道恶性肿瘤,死亡率排在恶性肿瘤的第二位。据最新的医学突破性研究表明,胃癌患者预后生存质量与病症分型、肿瘤分型存有较为密切的联系,而人类表皮生长因子受体2(HER2)在其中就起着信号传导的关键作用。HER2小分子酪氨酸激酶抑制剂、单克隆抗体均可以起到活性调节的效果。多年来靶向HER2药物治疗胃癌的临床试验已经多次证明,单克隆抗体联合一线的化疗类药物应用到胃癌患者的临床治疗,尤其是对于胃癌晚期患者,可以对患者的生存期起到显著改善效果。
作者 柳子川
出处 《中国现代药物应用》 2017年第12期134-135,共2页 Chinese Journal of Modern Drug Application
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