布地奈德与孟鲁司特钠联合治疗支气管哮喘的临床效果观察

Clinical observation of budesonide combined with montelukast sodium in the treatment of bronchial asthma

目的分析布地奈德与孟鲁司特钠联合治疗支气管哮喘的临床效果。方法选取我院2016年1月至12月收治的78例支气管哮喘患儿作为研究对象,按不同治疗方式将其分为研究组(39例)与对照组(39例)。对照组行常规治疗,研究组基于常规治疗行布地奈德与孟鲁司特钠联合治疗,比较两组肺功能指标改善情况、治疗总有效率及不良反应发生率。结果研究组患者的肺功能指标改善情况优于对照组,差异有统计学意义(P<0.05);研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05);研究组不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论布地奈德与孟鲁司特钠联合治疗支气管哮喘的效果显著,可改善支气管哮喘患儿的肺功能指标,减少不良反应,促进患儿快速康复,值得在临床治疗工作中推广应用。

Objective To analyze the clinical effect of combination of budesonide and montelukast sodium in the treatment of bronchial asthma. Methods Seventy-eight patients with bronchial asthma treated in our hospital from January to December in 2016 were divided into study group（39 cases） and control group（39 cases） according to different treatment methods. The control group adopted routine treatment, while the study group adopted budesonide combined with mon telukast sodium. The improvement of lung function indexes, total effective rate of treatment and incidence of adverse reactions were compared between the two groups. Results The improvement of lung function indexes in the study group was better than those in the control group（P〈0.05）. The total effective rate in the study group was higher than that in the control group（P〈0.05）. The incidence of adverse reactions in the study group was lower than that in the control group（P〈0.05）. Conclusion Combination of budesonide and montelukast sodium in the treatment of bronchial asthma is effective, it can improve the lung function indexes of bronchial asthma patients, reduce adverse reactions, promote children＇ rapid recovery, which is worthy of clinical application.