中国青年学生HIV和梅毒感染率Meta分析

HIV and syphilis prevalence among high school and college students in China:a meta-analysis

目的运用Meta分析综合评价中国青年学生艾滋病病毒(HIV)和梅毒的感染状况,并且分析其时间和地区分布。方法检索万方数据库、中国知网及PUBMED数据库,并通过相应检索策略收集关于中国青年学生HIV和梅毒感染率的调查文献。对其进行数据提取,运用R软件计算合并率,并进行发表偏倚的评估。结果共有27篇文献入选。2004-2014年,不同年份的HIV总体合并率,其结果变动在0~0.013%之间;计算梅毒总体合并率,其结果变动在0~0.17%之间。在各地区中,一类省份的合并HIV感染率(0.012%)高于二类、三类省份;合并梅毒感染率与HIV疫情分类省份间无明显关联,其结果变动在0.026%~0.056%之间。结论中国青年学生HIV、梅毒的合并感染率总体都处于上升趋势,控制该人群中HIV的感染和传播,对遏制中国艾滋病的流行有重要意义。亟须加强关于学生性行为和预防HIV、梅毒的教育及干预工作。

Objective To analyze the prevalence of HIV and syphilis, and their distribution in different regions and time among high school and college students in China. Methods Using WanFang database, CNKI, PuhMed, we collected information on prevalence of HIV/syphilis among Chinese high school students and used the R software to calculate the merger ratio, and assessed the publication bias. Results 27 studies were selected in total. The pooled prevalence rates of HIV and syphilis over the years varied between 0-0. 013 % and 0-0.17% respectively. In the high HIV prevalence provinces, the rate was 0. 012%, ranking top in China. There was no significant associa- tion of the pooled prevalence rates of HIV and syphilis over different types of the provinces. The syphilis Results varied between 0. 026%-0. 056%. Conclusion Both the pooled prevalence rates of HIV and syphilis among high school and college students were rising. It＇s vital to increase the awareness of HIV/syphilis prevention and inter- vention among the students.