期刊文献+

高剂量左旋甲状腺素治疗妊娠并甲状腺功能减退对患者血脂代谢及疗效影响 被引量:5

下载PDF
导出
摘要 目的:探讨高剂量左旋甲状腺素治疗妊娠并甲状腺功能减退对患者血脂(TC、TG、HDL-C、LDL-C)代谢及疗效(TSH)的影响。方法:选取2015年1月-2016年1月在我院就诊的172例妊娠并甲状腺功能减退患者,将其随机均分为观察组和对照组,各86例,观察组给予常规治疗联合高剂量左旋甲状腺素治疗,对照组给予常规治疗联合低剂量左旋甲状腺素治疗,分别于治疗前、后测定其TC、TG、HDL-C、LDL-C、TSH水平。结果:两组治疗前血清TC、TG、HDL-C、LDL-C、TSH水平差异无统计学意义(P>0.05);治疗后两组血清TC、TG、LDL-C、TSH水平较治疗前显著降低(P<0.05),血清HDL-C水平显著增高(P<0.05);治疗后观察组血清TC、TG、LDL-C、TSH水平较对照组显著偏低(P<0.05),血清HDL-C水平显著偏高(P<0.05)。结论:高剂量左旋甲状腺素在治疗妊娠并甲状腺功能减退患者时能较好地纠正异常血脂水平,并能较好地提高患者疗效。
出处 《医学理论与实践》 2017年第12期1807-1808,共2页 The Journal of Medical Theory and Practice
  • 相关文献

参考文献4

二级参考文献30

  • 1丰有吉,沈铿.妇产科学[M].北京:人民卫生出版社,2008.272-275.
  • 2Casey BM, Dashe JS, Wells CE, et al. Subclinical hypothyroidism and pregnancy outcomes [ J ]. Obstet Gynecol,2005,105 : 239 - 245.
  • 3Tian L, Gao C, Liu J, et al. Increased carotid arterial stiffness in sub- clinical hypothyroidism [ J ]. Eur J Intern Med,2010,21:560 - 563.
  • 4Leslie De Groot,Marcos Abalovich,Erik K. Alexander,Nobuyuki Amino,Linda Barbour,Rhoda H. Cobin,Creswell J. Eastman,John H. Lazarus,Dominique Luton,Susan J. Mandel,Jorge Mestman,Joanne Rovet,Scott Sullivan.Management of Thyroid Dysfunction during Pregnancy and Postpartum: An Endocrine Society Clinical Practice Guideline[J].The Journal of Clinical Endocrinology & Metabolism.2012(8)
  • 5Leung A M. Thyroid function in pregnancy[J]. J Trace Elem Med Bi- ol, 2012, 26(2-3):137-140.
  • 6薛辛.东儿科学[M].北京:人民卫生出版社,2008:24.
  • 7Wikner B N, Sparre L S, StiLler C O, et al. Maternal use of thyroid hormones in pregnancy and neconatal outcome [J]. Acta Obstet Gynecol Scand, 2008, 87(6):617-627.
  • 8Milanesi A, Brent G A. Management of hypothyroidism in preg- nancy [J]. Curr Opin Endocrinol Diabetes Obes, 2011, 18(5): 304-309.
  • 9YuanbinLi,ZhongyanShan,WeipingTeng,XiaohuiYu,YushuLi,ChenlingFan,XiaochunTeng,RuiGuo,HongWang,JiaLi,YanyanChen,WeiweiWang,MasausoChawinga,LiZhang,LiuYang,YaruZhao,TianyiHua.Abnormalities of maternal thyroid function during pregnancy affect neuropsychological development of their children at 25–30?months[J]. Clinical Endocrinology . 2010 (6)
  • 10Berbel Pere,Mestre José Luis,Santamaría Asunción,Palazón Inmaculada,Franco Ascensión,Graells Marisa,González-Torga Antonio,de Escobar Gabriella Morreale.Delayed neurobehavioral development in children born to pregnant women with mild hypothyroxinemia during the first month of gestation: the importance of early iodine supplementation. Thyroid : official journal of the American Thyroid Association . 2009

共引文献107

同被引文献39

二级引证文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部