3种世居高原民族部分生理指标调查及多因素分析

Investigation of physiological indicators and multivariate analysis of 3 kinds of native plateau national

目的调查分析世居高原藏族、塔吉克族、柯尔克孜族3种民族农牧民动脉血氧饱和度（SaO2）、血红蛋白（Hb）、血压等生理指标，初步探讨3种民族高原低氧适应特征。方法选择世居阿里高原（海拔4400m）藏族农牧民50例、喀喇昆仑山（海拔3700m）柯尔克孜族农牧民36例、帕米尔高原（海拔3200m）塔吉克族农牧民40例进行Sa02、Hb、血压等基本临床资料的调查。采用logistic逐步回归模型进行SaO2影响因素的多因素分析。结果3种民族农牧民Hb、血压水平比较差异均无统计学意义（P〉O．05），Sa02水平比较差异有统计学意义（P〈O．01）。Sa02的影响因素为民族、海拔高度、年龄等，差异有统计学意义（P〈O．01）。结论3种民族农牧民适应高原特征不同，但均不以增加Hb水平来增大携氧能力，藏族农牧民在高原低氧适应方面最优。

Objective Through survey and analysis of SaO2 , Hb and blood pressure physiological indexes have been conducted a- mong native plateau Tibetan, Tajik and Kirgiz,and preliminary discuss has then been conducted to explore the high altitude hypoxia adaptation of these three kinds of ethnic characteristics. Methods We chose samples from Native All plateau Tibetan （Altitude 4 400 m,n=50） ,Karakoram Kirgiz（Altitude 3 700 m,n=36） and Pamirs Tajik（Altitude 3 200 m,n=40） ,and then we conducted in- vestigation on SaO2, Hb,blood pressure and other basic clinical data. Stepwise logistic regression model was used to screen the po- tential influence factors of AD. Results Among three Nationalities,there were no significant difference between Hb and blood pres- sure（P〈0.05）;there were significant differences in SaO2 among three nationalities （P〈0.05）. Regression analysis showed that SaO2 might involve the following risk factors,including ethnic,altitude and age（P〈0.01）. Conclusion 3 kinds of ethnic have dif- ferent characteristics to adapt high altitude,while they do not increase Hb to increase the oxygen-carrying capacity. Among them, the Tibetans have the best adapt ability to high altitude hypoxia.