摘要
目的改进院内制剂芍黄通便合剂的质量标准。方法使用薄层色谱法定性分析鉴别芍黄通便舍剂中的白芍、大黄、白术三个药材,同时通过高效液相色谱法对芍药苷进行定量分析。结果薄层鉴别专属性强;芍药苷在0.2006~2.0060μg范围内与峰面积呈良好的线性关系(r=0.9995),平均回收率为100.2%,相对标准偏差(RSD)为2.25%(n-6)。结论所建方法简便、准确,能更好地控制芍黄通便合剂的质量。
Objective To improve the quality standard of Shaohuang laxative agent. Methods Radix paeoniae alba,Rheum and Atractylodes were identified qualitatively by TLC;the content of Paeoniflorin was determined by HPLC. Results TLC were distinct and highly specific ; The linear range of Paeoniflorin was from 0. 200 6 to 2. 006 0 μg(r=0. 999 5)with an average recovery of 100. 2 %,RSD= 2.25 % (n=6). Conclusion The method is convenient and reliable, which could be better for quality control of Shao- huang laxative agent.
出处
《重庆医学》
CAS
北大核心
2017年第A01期38-40,共3页
Chongqing medicine
基金
四川省科技厅应用基础计划项目(2015JY0049).