慢性阻塞性肺疾病急性加重期患者血糖、血脂的表达特征

Expression of blood glucose and lipid in patients with acute exacerbation of chronic obstructive pulmonary disease

目的研究慢性阻塞性肺疾病急性加重期（AECOPD）患者血糖、血脂的表达特征。方法选取金坛区中医医院2013～2015年收治的AECOPD患者142例设为观察组（重度组70例，轻度组72例），选取同期在金坛区中医医院进行健康体检的健康体检者100例设为对照组，比较两组研究对象血糖、血脂表达特征。结果重度组、轻度组患者糖化血红蛋白、空腹血糖、餐后2小时血糖与对照组比较差异均有统计学意义（P〈0．05）；重度组患者三酰甘油（TG）、高密度脂蛋白胆固醇（HDL-c）、低密度脂蛋白胆固醇（LDL-C）与对照组比较差异均有统计学意义（P〈0．05），轻度组患者TG、HDL-C与对照组比较差异均有统计学意义（P〈0．05）。结论AECOPD患者会出现明显的血糖、血脂相关指标的改变，观察血糖、血脂相关指标变化对判断患者病情、预后具有重要的临床价值。

Objective To study the expression of blood glucose and lipids in patients with acute exacerbation of chronic obstruc- tive pulmonary disease（AECOPD）. Methods 142 patients with acute exacerbation of chronic obstructive pulmonary disease in our hospital were selected as the observation group（70 cases in the severe group and 72 cases in the mild group）. 100 healthy subjects in the same hospital were selected as controls Group, the blood glucose, blood lipid characteristics of the two groups were compared. Results There were significant differences in glycosylated hemoglobin,fasting blood glucose and postprandial 2-hour blood glucose of severe group,mild group and control group, （P〈0.05）;in severe group and control group,C and LDL-C,and there were signifi- cant differences in TG and HDL-C expression between the mild group and the mild group（P〈0.05）. Conclusion The patients with acute exacerbation of chronic obstructive pulmonary disease will have obvious changes of blood sugar and blood lipid. It is important to observe the change of blood sugar and blood lipid related indexes in patients with prognosis and clinical judgment.