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联合检测血清HE4和CAl25在卵巢癌早期诊断中的意义 被引量:2

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摘要 目的探析联合检测血清人附睾分泌蛋白(HE4)和癌抗原125(CAl25)在卵巢癌早期诊断中的意义。方法选取2014年10月至2016年6月该院收治的卵巢疾病患者165例作为研究对象,根据术后病理检查结果分为甲组(85例)和乙组(83例)。甲组为卵巢癌患者,乙组为卵巢良性病变患者。采用电化学发光法检测患者血清HE4、CAl25水平,观察比较两组患者血清HE4、CAl25水平。结果甲组患者血清HE4、CAl25水平均明显高于乙组,差异均有统计学意义(P〈O.05)。单项检测血清HE4的灵敏度、特异性分别为80.5%、81.9%,单项检测血清cAl25的灵敏度、特异性分别为70.7%、67.5%,二者联合检测的灵敏度、特异性分别为91.5%、91.6%。结论血清HE4是一种较理想的卵巢肿瘤标志物,在卵巢癌早期诊断中联合检测血清HE4和CAl25的临床价值较高,值得临床广泛推广应用。
出处 《重庆医学》 CAS 北大核心 2017年第A01期265-266,共2页 Chongqing medicine
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