艾灸联合艾司西酞普兰以及经颅磁刺激(rTMS)治疗脑卒中后抑郁的临床观察

Clinical observation of moxibustion combined with Ai Sciplan and transcranial magnetic stimulation( r TMS) in the treatment of post stroke depression

目的:观察分析艾灸联合艾司西酞普兰、经颅磁刺激治疗脑卒中后抑郁的临床疗效。方法:70例脑卒中后抑郁患者,按照治疗方式不同采用数字随机法分为观察组与对照组,各35例。观察组患者给予艾灸、艾司西酞普兰联合经颅磁刺激治疗,对照组患者给予艾司西酞普兰治疗,对比两组患者的治疗效果。结果:观察组患者的临床疗效显著优于对照组(P<0.05);治疗前,两组患者的HAMD与ADL评分对比差异无统计学意义(P>0.05);治疗4周后,两组患者的HAMD评分显著低于治疗前(P<0.05),ADL评分显著高于治疗前(P<0.05);且观察组患者的HAMD评分显著低于对照组(P<0.05),ADL评分显著高于对照组(P<0.05)。结论:艾灸联合艾司西酞普兰、经颅磁刺激治疗脑卒中后抑郁的临床疗效良好,具有临床推广使用价值。

Objective： To observe the clinical efficacy of moxibustion combined with Ai Sciplan and transcranial magnetic stimulation in the treatment of post -stroke depression. Methods： 70 patients with post -stroke depression were randomly divided into the observation group and the control group according to different treatment methods, each with 35 cases. Patients in the observation group were treated with moxibustion and escitalopram combined with transcranial magnetic stimulation, while the control group was treated with Ai Sciplan. The therapeutic effects of the two groups were compared. Results： The clinical observation group were significantly higher than those in patients with the control group （ P 〈 0. 05 ） ; before treatment, there was no significant difference between HAMD and ADL scores of the two groups of patients （P 〉 0. 05 ） ; after 4 weeks of treatment, two groups of patients with HAMD score was significantly lower than that before treatment （P 〈0. 05）, ADL score was significantly higher than that before treatment （P 〈0. 05）. Conclusion：The clinical curative effect of moxibustion combined with Ai Sciplan and transcranial magnetic stimulation in the treatment of post stroke depression is good.