未足月胎膜早破不同孕周的处理方式及对母儿结局的影响

Study on Handling Methods of Preterm Premature Rupture of the Membrane in Different Pregnant Weeks and Effect on the Maternal and Infant Outcome

目的探讨不同孕周未足月胎膜早破(PPROM)的临床处理方式及对母儿结局的影响。方法方便选取2011年3月—2016年6月该院收治的138例PPROM患者的临床资料,根据孕周不同将入选病例分为A组和B组。对比观察两组不同保胎时间、不同分娩方式下的母儿结局。结果 A组保胎≥24 h者新生儿死亡率(14.3%)低于保胎<24 h者(39.3%),B组保胎<24 h者绒毛膜羊膜炎(6.7%)、产褥感染(2.2%)、新生儿窒息/NRDS(8.8%)和新生儿死亡(4.4%)均低于保胎≥24 h者(P<0.05)。结论 PPROM患者应根据实际孕周及胎儿状况科学延长保胎时间、选择合适的分娩方式,以减少母体并发症和新生儿死亡风险。

Objective To study the handling methods of preterm premature rupture of the membrane in different pregnant weeks and effect on the maternal and infant outcome.Methods 138 cases of PPROM patients admitted and treated in our hospital from March 2011 to June 2016 were convenient selected and divided into two groups according to different the pregnant weeks,and the maternal and infant outcomes under different tocolysis time and different delivery methods were compared and observed.Results In the group A,the death rate of newborns whose tocolysis ≥24 h was lower than that of newborns whose ocolysis 24 h（14.3% vs 39.3%）,in the group B,the incidence rate of chorioamnionitis（6.7%）,puerperal infection（2.2%）,neonatal asphyxia/NRDS（8.8%） and death rate of newborns whose ocolysis 24 h in the group B were lower than those in patients whose tocolysis≥24 h（4.4%）（P〈0.05）.Conclusion The PPROM patients should scientifically prolong the tocolysis time and select the proper delivery method according to the practical pregnant weeks and fetal situation in order to reduce the maternal and infant complications and death risks of newborns.