异搏定和胺碘酮治疗阵发性室上性心动过速的临床效果

Clinical Effect of Verapamil and Amiodarone in Treatment of Paroxysmal Supraventricular Tachycardia

目的探讨异搏定和胺碘酮治疗阵发性室上性心动过速的临床效果。方法方便选取2015年1月—2016年1月该院收治的阵发性上性心动过速患儿88例,按照随机数字表法,分为对照组(n=44)与观察组(n=44)。对照组采用异搏定进行治疗,观察组采用胺碘酮进行治疗,比较两组治疗效果及不良反应发生率。结果经过相应药物治疗后,对照组治疗总有效率为88.64%,观察组治疗总有效率为93.18%,两组差异无统计学意义(P>0.05);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论异搏定和胺碘酮治疗阵发性室上性心动过速均具有显著治疗效果,但相较异搏定,胺碘酮的不良反应更少,因此具有更为显著的临床应用价值。

Objective To study the clinical effect of verapamil and amiodarone in treatment of paroxysmal supraventricular tachycardia. Methods Convenient selection 88 cases of children with paroxysmal supraventricular tachycardia admitted and treated in our hospital from January 2015 to January 2016 were selected and randomly divided into two groups with 44 cases in each, the control group were treated with verapamil, while the observation group were treated with amiodarone, and the treatment effect and incidence rate of adverse reactions were compared between the two groups. Results After the treatment,the difference in the total effective rate between the control group and the observation group was not statistically significant（88.64% vs 93.18%）（P〈0.05）, and the incidence rate of adverse reactions in the observation group was lower than that in the control group, and the difference was statistically significant（ P〈0. 05）. Conclusion The effect of verapamil and amio-darone in treatment of paroxysmal supraventricular tachycardia is obvious, but the adverse reactions of amiodarone are fewer than those of verapamil, therefore, it is worth clinical application.