直肠癌低位前切除术后吻合口漏发生的危险因素和临床防治方法分析

Analysis of risk factors and clinical prevention and treatment of anastomotic leakage after anterior resection of rectal cancer

目的研究并探讨直肠癌低位前切除术后吻合口漏发生的危险因素及临床防治方法。方法选取98例直肠癌低位前切除术患者作为研究对象,对其临床资料进行回顾性分析,统计直肠癌低位前切除术患者术后发生吻合口漏的例数,根据术后是否发生吻合口漏分为吻合口漏组、对照组,对两组临床资料进行分析,进一步分析导致直肠癌低位前切除术后发生吻合口漏的危险因素。结果术后吻合口漏发生率为23.47%,经单因素、多因素Logistics回归分析后发现,直肠癌低位前切除术后发生吻合口漏的危险因素主要为术前体重指数、糖尿病、术前血清白蛋白、肠道准备、肿瘤TNM分期。结论直肠癌低位前切除术后发生吻合口漏主要和患者术前自身因素、术前肠道准备及肿瘤进展有关,临床上应严格掌握吻合口漏发生的相关危险因素,在围手术期实施针对性防治措施。

Objective To study and explore the risk factors and clinical prevention and treatment of anastomotic leakage after anterior resection of rectal cancer.Methods A total of 98 patients with low anterior resection of rectal cancer were enrolled in our hospital from January 2013 to December 2016.The clinical data were analyzed retrospectively.The patients underwent anastomosis after low anterior resection of rectal cancer The number of cases of oral leakage,according to whether the occurrence of anastomotic leakage is divided into anastomotic leakage group,the control group,the two groups of clinical data analysis,further analysis of leading anterior resection of rectal cancer after anastomotic leakage risk factors.Results The incidence of postoperative anastomotic leakage was 23.47%.The risk factors of anastomotic leakage after rectal cancer low anterior resection were mainly preoperative weight index,diabetes mellitus,preoperative Serum albumin,intestine preparation,tumor TNM staging.Conclusion Anastomotic leakage after anterior resection of rectal cancer is related to the factors of preoperative operation,preoperative bowel preparation and tumor progression,and the relevant risk factors of anastomotic leakage should be strictly controlled in clinic.Targeted prevention and control measures.