放射治疗对鼻咽癌患者听功能损害因素研究

Study on the factors of hearing impairment in patients with nasopharyngeal carcinoma treated by radiotherapy

目的:探讨放射治疗对鼻咽癌患者听功能的影响。方法:收治鼻咽癌患者120例为观察组,比较放射治疗前后的电测听相关检查结果。选取健康人120例为对照组,对比两组听功能情况。结果:放疗半年后,观察组中度以上听力损伤所占比例75.0%,与对照组相比,差异有统计学意义(P<0.05);治疗1年后,观察组中度损伤与治疗半年后相比有所缓解,但仍高于治疗前(P<0.05)。结论:放疗治疗会对鼻咽癌患者的听功能造成明显不利影响,需加以关注,从而减少损伤,提高预后效果。

Objective:To investigate the effect of radiotherapy on auditory function in patients with nasopharyngeal carcinoma.Methods:120 patients with nasopharyngeal carcinoma were selected as the observation group.We compared the results of the audiometry before and after radiotherapy.120 healthy people were selected as the control group.We compared the auditory function of the two groups.Results:After half a year of radiotherapy,in the observation group,the proportion of moderate to severe hearing loss was 75%,which was significantly different from that of the control group(P<0.05).After 1 year of treatment,compared with six months after treatment,in the observation group,moderate damage was relieved,but it was still higher than before treatment(P<0.05).Conclusion:Radiotherapy can cause significant adverse effects on auditory function of patients with nasopharyngeal carcinoma,and we need to pay attention to it,so as to reduce the damage and improve the prognosis.