盐酸莫西沙星片治疗慢性阻塞性肺疾病急性加重期门诊患者的临床疗效观察

Clinical efficacy of moxifloxacin hydrochloride tablets in the treatment of outpatients with acute exacerbation of chronic obstructive pulmonary disease

目的:探讨盐酸莫西沙星片治疗慢性阻塞性肺疾病急性加重期(AECOPD)的临床疗效。方法:收治AECOPD的门诊患者121例,并随机分为试验组和对照组。试验组给予盐酸莫西沙星片,对照组给予阿莫西林克拉维酸钾片,观察比较两组临床疗效和不良事件的发生率。结果:治疗10 d后观察,试验组临床疗效明显高于对照组,而不良事件发生率却明显低于对照组,差异有统计学意义(P<0.05)。结论:盐酸莫西沙星片治疗AECOPD具有良好的疗效,且安全性好。

Objective:To investigate the clinical effect of moxifloxacin hydrochloride tablets in the treatment of outpatients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:121 outpatients with acute exacerbation of chronic obstructive pulmonary disease were selected.They were randomly divided into the experiment group and the control group.The experiment group were given moxifloxacin hydrochloride tablets,and the control group were given amoxicillin and clavulanate potassium tablets.The clinical efficacy and incidence of adverse events were observed and compared between groups.Results:After 10 days of treatment,the clinical efficacy of the experimental group was significantly higher than that of the control group,but the incidence of adverse events was significantly lower than that of the control group,and the differences were statistically significant(P<0.05).Conclusion:Moxifloxacin hydrochloride tablets has a good therapeutic effect in the treatment of AECOPD,and it has good security.