PD-1/PD-L1在食管鳞癌中的研究进展

Research progress of PD-1/PD-L1 in esophageal squamous cells

食管癌的发病率和死亡率均较高,也是最难治疗和治愈的恶性肿瘤之一。当前,免疫检查点抑制剂在肿瘤治疗中取得了突破进展,相关研究已成为热点,针对免疫检查点"程序性死亡分子1"(PD-1)及其配体PD-L1抗体的临床研究也正在广泛开展,本文就PD-1/PD-L1在食管鳞癌中的研究进展做一综述。

Esophageal cancer morbidity and mortality are high, but it is also the most difficult to treat and cure one of the malignant tumors. At present, immunoinhibitors have made breakthroughs in the treatment of canc-er ,and related research, Which have become a hot field for the clinical study of immunological checkpoint u proce-dural death molecule V （PD - 1 ）and its ligand PD - L1 antibody. In this paper,we reviewed the progress of PD-1/PD - L1 in esophageal squamous cell carcinoma.