基于现代文献从“虚、实”论脂肪肝与血脂四项的关系

Discussion on the relationship between fatty liver and blood lipid Based on the modern literature from "Virtual and real"

目的:基于近10年的文献数据,从"虚证、实证"角度探讨脂肪肝与血脂4项的关系,以协助临床诊疗。方法:以"脂肪肝""中医""证"等为主题词,系统检索中国知网、维普期刊、万方数据近10年来所有相关文献,选取其中脂肪肝中医辨证分型下有血脂4项指标具体数据的临床研究的文献报道进行文献研究,使用Epi-Data建立脂肪肝虚证、实证与血脂4项指标的文献数据库,运用Excel软件对数据进行描述性统计分析。结果:符合纳入分析标准的文献有32篇,涉及病例数共计5865例。虚证患者2084例,实证患者2655例。虚实夹杂及其他证型患者暂不纳入本研究。虚证、实证脂肪肝患者的血脂4项指标的均值有所不同,反映两类脂肪肝患者的脂代谢受损程度有所差别。结论:虚证脂肪肝患者以肝郁脾虚证常见,实证以湿热内蕴证常见。虚证患者多表现为高水平的HDL-c、LDL-c,实证患者多表现为高水平的TC、TG。

Objective： To discuss the relationship between fatty liver and blood lipid Based on the modern literature from Virtual and real. Methods： Taking ＂fatty liver＂, ＂traditional Chinese medicine＂ and ＂syndrome＂ as the key words, all the relevant literature in recent 10 years were retrieved through China HowNet, Wanfang Data and weipu system , using literature database Epi-Data to establish indicators for fatty liver de- ficiency and demonstration syndrom and blood lipid, the data were analyed by using Excel software. Results： There were 32 articles that met the in- clusion criteria, involving a total of 5865 cases. Deficiency syndrome in 2084 cases, positive patients in 2655 cases. Other syndrome types were not included in this study. The mean of four indexes of blood lipid in patients with deficiency syndrome and positive fatty liver were different, which showed that the degree of lipid metabolism in the patients with the two types of fatty liver was different. Conclusion： Deficiency syndrome in patients with more performance for a high level of HDL-c and LDL-c, empirical patients characterized by high levels of TC, TG.