静脉溶栓治疗脑梗死病人生存状况的相关因素研究

Study on the related factors of survival in the elderly patients with cerebral infarction receiving intravenous thrombolysis

目的探究静脉溶栓治疗老年脑梗死病人生存状况的相关因素。方法选取在我院接受治疗的100例老年脑梗死病人,将所有病人根据生存状况以及Rankin评分分为2组,分别是生存组47例,出现功能障碍以及死亡现象并且Rankin评分>2分的53例病人为未生存组。比较2组病人治疗过程中的各项临床指标的差异,对病人的各项临床指标进行回归性分析。结果生存组病人发病至溶栓时间、高血压史、高血脂史、吸烟、酗酒、牛津郡社区卒中计划(oxfordshire community stroke project,OCSP)分型和TOASP分型各项数据均和未生存组病人差异有统计学意义(P<0.05),多因素Logistic回归分析结果显示,以上指标均为病人生存的独立危险因素。结论影响静脉溶栓治疗脑梗死病人生存状况的相关因素很多,包括发病到溶栓时间、高血压、高血脂、吸烟、酗酒、OCSP分型和TOASP分型。

Objective To explore the related factors of survival in the elderly patients with cerebral infarction treated by intravenous thrombolysis. Methods 100 patients with cerebral infarction who received intravenous thrombolysis in our hospital were enrolled in this study. All patients were divided into two groups according to the survival condition and the Rankin score, the survival group with 47 cases, and the non-survival group with 53 cases. The clinical indicators of the two groups in treatment process were analyzed and compared. Results The time from onset to thrombolysis, history of hypertension, hyperlipidemia, smoking, alcohol abuse, oxfordshire community stroke project （OCSP） type and TOASP type in survival group showed significant differences from those in non-survival group （P〈0. 05 ）. Logistic regression analysis showed that the time from onset to thrombolysis, history of hypertension, hyperlipidemia, smoking, alcohol abuse, OCSP type and TOASP type were independent risk factors of death in the elderly patients with cerebral infarction treated by intravenous thrombolysis. Conclusions There are many factors affecting the survival of patients with cerebral infarction treated by intravenous thrombolytic therapy, including the time from onset to thrombolysis, hypertension, hyperlipidemia, smoking, alcohol abuse, OCSP type and TOASP type.