禁食时间与消化性溃疡出血患者临床结局相关性分析

Relationship between fasting time and clinical outcomes in patients with peptic ulcer bleeding

目的探讨禁食时间长短对消化性溃疡出血患者临床结局的影响,进而评估消化性溃疡出血患者早期是否需严格禁食。方法回顾性分析152例消化性溃疡出血患者的临床资料,通过回归模型校正混杂因素,分析禁食时间是否是消化性溃疡出血患者临床结局指标(住院时间、住院费用、院内死亡、持续出血、再出血)的显著性影响因素。结果禁食时间不是消化性溃疡出血患者临床结局指标(住院时间、住院费用、持续出血、再出血)的显著性影响因素。本研究中无院内死亡病例,无法分析禁食时间对消化性溃疡出血患者院内病死率的影响。结论消化性溃疡出血患者早期无需严格禁食。

Objective To investigate the relationship between fasting time and clinical outcomes in patients with peptic ulcer bleeding. Then to assess whether fasting must be required in the early phase of acute peptic ulcer bleeding.Methods The clinical data of 152 patients with peptic ulcer bleeding were analyzed retrospectively. To analyze whether fasting time had effect on length of hospital stay,hospital costs,in-hospital mortality,continued bleeding and re-bleeding after correcting confounding factors by regression analysis. Results Fasting had no significant effect on length of hospital stay,hospital costs,continued bleeding and re-bleeding in patients with peptic ulcer bleeding. Nobody died in hospital,so the relationship between fasting time and in-hospital mortality was not analyzed. Conclusion Early oral feeding is safe and feasible in the early phase of acute peptic ulcer bleeding.