Q开关1064 nm Nd:YAG激光治疗黄褐斑所致点状色素减退:2年随访研究

Mottled hypopigmentation induced by Q-switched 1064 nm Nd:YAG laser in the treatment of melasma:a two-years follow-up study

目的:了解大光斑低能量模式Q开关1064 nm激光治疗黄褐斑后所致点状色素减退恢复情况。方法:对大光斑低能量模式Q开关1064 nm Nd:YAG激光治疗5次以上的180例黄褐斑患者随访2年。结果:15例出现点状色素减退(8.33%),2年后1例痊愈,2例有改善,13例无变化。结论:大光斑低能量Q开关1064 nm激光治疗黄褐斑所致的点状色素减退斑可持续2年以上。

Objective： To investigate the development of the mottled hypopigmentation induced by low-fluence large-spot-size Q-switched 1064 nm Nd：YAG laser in the treatment of melasma.Methods： One hundred and eighty patients with melasma treated with the Q-switched 1064 nm Nd：YAG laser for more than 5 times were followed up for 2 years.Results： Out of 180 patients with melasma, fifteen patients （8.33%） presented with mottled hopopigmentation.The hypopigmentation lesions recoveried in one case after 2 years, improvement in 2 and no change in 13.Conclusion： The mottled hypopigmentation induced by the low-fluence large-spot-size Q-switched 1064 nm Nd：YAG laser can persist for more than two years.