干细胞移植治疗脊髓损伤的研究

Stem cell transplantation in the treatment of spinal cord injury

脊髓损伤是一种由外伤、感染、缺血或相关病变累及引起的难治性中枢神经系统疾病,具有极高的致残率和致死率。传统的营养神经药物、理疗及对症治疗效果欠佳,已有动物研究和临床试验证明干细胞移植是一项有望修复脊髓损伤的策略。研究干细胞治疗脊髓损伤的修复机制、现状及最新进展可为脊髓损伤开辟全新的治疗思路。

Spinal cord injury （SCI） is an intractable disease of central nervous system, caused by traumatic assault, infection or allied lesions, with an extremely high rate of disability and fatality. While the effect of conventional neurotrophic drugs, physical treatments and heteropathy are unfavorable, the application of stem cell transplantation to SCI may be a promising therapeutic strategy that has been proved by a few animal studies and clinical trials. To study the repair mechanism of stem cells for spinal cord injury,present situationand the latest progress can open up a new treatment for spinal cord injury.