CT引导下经皮肺穿刺活检对肺局灶性磨玻璃影的诊断价值

Diagnostic value of CT-guided percutaneous transthoracic needle biopsy on pulmonary focal ground glass opacity

目的评价CT引导下经皮肺穿刺活检(PTNB)对肺局灶性磨玻璃影(GGO)的诊断价值。方法回顾性分析CT引导下PTNB 53例肺局灶性GGO患者的临床资料,根据穿刺活检病理和胸腔镜手术病理对照,比较CT引导下对PTNB>8mm/≤8mm局灶性GGO的活检病理准确率和部分实性GGO/纯GGO的病理准确率。结果 CT引导下PTNB对>8mm局灶性GGO活检病理准确率为91.11(41/45)/≤8mm局灶性GGO活检病理准确率为37.50(3/8);两者差异有统计学意义(x^2=10.306,P<0.05)。部分实性GGO的活检病理准确率为87.18(34/39),纯GGO的活检病理准确率为71.43(10/14);两者差异无统计学意义(x^2=3.102,P>0.05)。结论 CT引导下PTNB对于>8mm肺局灶性GGO具有较高的诊断价值。

Objective To estimate the diagnostic value of CT guided percutaneous transthoracic needle biopsy（ PTNB） on pulmonary focal ground glass opacity（ GGO）. Methods The clinical data of 53 patients with pulmonary focal GGO underwent CT guided PTNB were analyzed retrospectively,the biopsy pathology and thoracoscope surgery pathology were compared,the accuracy of CT guided PTNB between 8 mm ≤ 8 mm focal GGO lesions and part-solid GGO pure GGO were compared. Results The pathological accuracy of CT guided PTNB was 91. 11%（ 41/45） on the 8 mm group,and that was 37. 50%（ 3/8）on the ≤ 8 mm group focal GGO; there was significant difference between the 2 groups（ x^2= 10. 306,P〈0. 05）. The pathological accuracy of Part-solid GGO was 87. 18%（ 34/39）,that of pure GGO was 71. 43（ 10/14）; there was no significant difference between the 2 groups（ x^2= 3. 102,P〈0. 05）. Conclusion CT guided PTNB for pulmonary 8 mm focal GGO has high diagnostic value.