低温等离子射频手术治疗儿童OSAHS的术中创伤程度及术后语音功能评估

Evaluation of the intraoperative trauma degree and postoperative speech function of lowtemperature plasma radiofrequency surgery treatment of children with OSAHS

目的:评估低温等离子射频手术治疗儿童OSAHS的术中创伤程度及术后语音功能。方法:OSAHS患儿118例按照随机数表法分为:接受常规手术治疗的对照组、接受低温等离子射频手术治疗的观察组各59例。术前、术后24h,测定两组血清中应激激素、急性时相蛋白、炎症因子含量,评估语音功能参数水平。结果:术前,两组血清中应激激素、急性时相蛋白、炎症因子含量,语音功能参数水平差异无统计学意义(P>0.05)。术后24h,观察组血清中应激激素ACTH、Ang-2、NE、Cor含量低于对照组,血清中急性时相蛋白HP、CER、PA含量低于对照组,血清中炎症因子IL-1、IL-4、IL-27、TNF-α含量低于对照组(P<0.05);观察组的语音功能参数NNE、NHR水平高于对照组(P<0.05)。结论:低温等离子射频手术用于儿童OSAHS的治疗,较常规手术创伤小、对患儿术后语音程度的提高程度大。

Objective：To evaluate the intraoperative trauma degree and postoperative speech function of low-temperature plasma radiofrequency surgery treatment of children with OSAHS.Methods：118children with OSAHS were divided into the control group（n=59）who received general surgery and the observation group（n=59）who received the low-temperature plasma radiofrequency surgery according to the random number table.Before operation and 24 hafter operation,serum levels of stress hormones,acute phase proteins and inflammatory markers of two groups of children were determined,and the speech function parameter levels were assessed.Results：Before operation,differences in serum contents of stress hormones,acute phase proteins and inflammatory factors as well as speech function parameter levels were not statistically significant between two groups of patients（P〈0.05）.24 hafter operation,serum stress hormones ACTH,Ang-2,NE and Cor contents of observation group were lower than those of control group,serum acute phase proteins HP,CER and PA contents were lower than those of control group,and serum inflammatory factors IL-1,IL-4,IL-27 and TNF-αcontents were lower than those of control group（P〈0.05）;speech function parameters NNE and NHR levels of observation group were higher than those of control group（P〈0.05）.Conclusion：Compared with routine surgery,low-temperature plasma radiofrequency surgery treatment of children with OSAHS causes less surgical trauma and more greatly improves the postoperative speech level.