期刊文献+

伐尼克兰戒烟研究进展 被引量:2

Research progress of varenicline in smoking cessation
原文传递
导出
摘要 伐尼克兰作为一种专门针对成人戒烟的处方药在中国上市已经8年有余。临床实践中伐尼克兰戒烟的有效性已经得到广泛肯定,对其安全性的研究,近年也取得了更深入的发展,在新研究成果的支撑之下,欧美已先后取消伐尼克兰安全警告标签。本文综述了伐尼克兰戒烟有效性及安全性的相关文献,以期澄清用药疑虑,促进合理用药,提高戒烟成功率。 Varenicline as a prescription drug for adults to quit smoking has been listed in the China market for more than 8 years. In clinical practice, the smoking cessation effectiveness of varenicline has been widely recognized, and research on its safety in recent years has also made more in-depth development. Under the support of new study results the Europe and the United States has canceled varenicline safety warning label. This paper reviewed the relevant literature of smoking cessation efficacy and safety of varenicline, in order to clarify the doubts, improve the rational use of drugs, and improve the success rate of smoking.
出处 《中国新药与临床杂志》 CSCD 北大核心 2017年第6期324-329,共6页 Chinese Journal of New Drugs and Clinical Remedies
关键词 戒烟 伐尼克兰 治疗结果 安全 临床研究 smoking cessation varenicline treatment outcome safety clinical trial
  • 相关文献

参考文献8

二级参考文献89

  • 1杨功焕,马杰民,刘娜,周灵妮.中国人群2002年吸烟和被动吸烟的现状调查[J].中华流行病学杂志,2005,26(2):77-83. 被引量:1054
  • 2陈晋东,赵靖平,国效峰,李乐华,罗琼,薛志敏,孙学礼,王高华,陈远光.安非他酮缓释片戒除尼古丁依赖的多中心随机双盲对照试验[J].中国新药与临床杂志,2006,25(3):161-164. 被引量:9
  • 3XIAO Y, LV Y, ZHANG X, et al. The pharmacokinetics and tolerability profile of varenicline in healthy Chinese volunteers[J]. Int J Clin Pharmacol Ther, 2009, 47(4) : 246-254.
  • 4WANG C, XIAO D, CHAN KP, et al. Varenicline for smoking cessation: a placebo-controlled, randomized study[J]. Respirology, 2009, 14(3): 384-392.
  • 5KASLIWAL R, WILTON LV, SHAKIR SA. Safety and drug utilization profile of varenicline as used in general practice in England: interim resul, ts from a prescription-event monitoringstudy[J]. Drug Saf, 2009, 32(6) : 499-507.
  • 6CAHILL KE, STEAD LY, LANCASTER TM. A preliminary benefit-risk assessment of varenicline in smoking cessation [J]. Drug Saf, 2009, 32(2): 119-135.
  • 7FOULDS JN. The neurobiological basis for partial agonist treatment of nicotine dependence: varenicline[J]. Int J Clin Pract, 2006, 60(5): 571-576.
  • 8porFI'S LA, GARWOOD CL. Varenicline: the newest agent for smoking cessation[J]. Am J Health Syst Pharm, 2007, 64 (13) : 1381-1384.
  • 9OBACH RS, REED-HAGEN AE, KRUEGER SS, et al. Metabolism and disposition of varenicline, a selective alpha4- beta2 acetylcholine receptor partial agonist, in vivo and in vitro [J]. Drug Metab Dispos, 2006, 34( 1 ) : 121-130.
  • 10TONSTAD SA, TφNNESEN PP, HAJEK PR, et al. Effect of maintenance therapy with varenicline on smoking cessation: a randomized controlled trial[J]. JAMA, 2006, 296(1 ): 64-71.

共引文献26

同被引文献43

引证文献2

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部