硝苯地平联合硫酸镁治疗妊娠期高血压的临床效果及预后被引量：1

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摘要目的研究硝苯地平联合硫酸镁对妊娠期高血压(HDCP)的治疗效果及预后影响。方法选取2014年9月至2016年8月在兰考第一医院治疗的妊娠期高血压患者102例,随机数字表法分为两组,各51例。对照组予以硫酸镁治疗,观察组予以硫酸镁+硝苯地平治疗。统计对比两组临床疗效及治疗后异常妊娠发生情况。结果治疗后两组临床治疗有效率比较,观察组高于对照组,差异有统计学意义(χ~2=6.331,P<0.05);治疗后两组异常妊娠发生率比较,观察组低于对照组,差异有统计学意义(χ~2=5.299,P<0.05)。结论硫酸镁联合硝苯地平治疗妊娠期高血压可提高临床疗效,并改善预后效果。

作者王俊莲

机构地区兰考第一医院妇科

出处《河南医学研究》 CAS 2017年第11期2051-2052,共2页 Henan Medical Research

关键词硝苯地平硫酸镁妊娠期高血压

分类号 R714 [医药卫生—妇产科学]

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1魏晓红,张宇骄,李爱玲,傅晓冬.硫酸镁联合川芎嗪治疗妊娠期高血压有效性和安全性的Meta分析[J].中国全科医学,2016,19(32):3966-3972. 被引量：27
2李介岩,张为远,王欣,邹丽颖.硫酸镁应用对妊娠期高血压疾病患者胎盘中基质金属蛋白酶-9和水通道蛋白-9表达的影响[J].中华医学杂志,2016,96(30):2421-2423. 被引量：30
3李广隽,刘晓巍,武绍文,赵娜,徐晖.硫酸镁联合硝苯地平治疗中重度妊娠高血压综合征患者的疗效观察[J].现代生物医学进展,2015,15(25):4896-4898. 被引量：41
4张纯萍,朱叶,黄炜.硫酸镁联合硝苯地平治疗妊娠期高血压疾病的效果评价[J].中国妇幼保健,2015,30(15):2461-2462. 被引量：40

二级参考文献59

1曹泽毅.妇产科学[M].北京:人民卫生出版社,2010:82-87.
2Huang X, Tan H, Li X, et al. Maternal chronic HBV infection would not increase the risk of pregnancy-induced hypertension-results from pregnancy cohort in Liuyang rural China [J]. PLoS One, 2014, 9(12): el 14248.
3Naito T, Kubono N, Degnchi S, et al. Amlodipine Passage into Breast Milk in Lactating Women with Pregnancy-Induced Hypertension and Its Estimation of Infant Risk for Breastfeeding [J]. J Hum Lact, 2015, 31 (2): 301-306.
4Rojo CW, Salazar PM, Parra JZ, et al. Circadian rhythm of blood pressure in patients with chronic hypertension and pregnancy [J]. Ginecol Obstet Mex, 2014, 82(9): 604-612.
5Ephraim R, Osakunur D, Denkyira S, et al. Serum calcium and magnesium levels in women presenting with pre-eclampsia and pregnancy-induced hypertension: a case, control study in the Cape Coast metropolis, Ghana[J]. BMC Pregnancy Childbirth, 2014, 14( 1): 390.
6Kemse NG, Kale AA, Joshi SR. A combined supplementation of omega-3 fatty acids and micronutrients (folio acid, vitamin B12) reduces oxidative stress markers in a rat model of pregnancy induced hypertension[J]. PLoS One, 2014, 9(11): el 11902.
7Aslani A, Tara F, Ghalighi L, et al. Impact of computer-based pregnancy-induced hypertension and diabetes decision AIDS on empowering pregnant women [J]. Healthc Inform Res, 2014, 20(4): 266-71.
8Kazemian E, Sotoudeh G, Dorosty AR, et al. Maternal obesity and energy intake as risk factors of pregnancy-induced hypertension among Iranian women[J]. J Health Popul Nutr, 2014, 32(3): 486-493.
9Watanabe K, Kimura C, Iwasaki A, et al. Pregnancy-induced hypertension is associated with an increase in the prevalence of cardiovascular disease risk factors in Japanese women[J]. Menopause, 2014, 10[Epub ahead of print].
10Tain YL, Huang LT, Lee CT, et al. Maternal citrulline supplementation prevents prenatal N(G)-nitro-L-arginine-methyl ester (L-NAME)-induced programmed hypertension in rats [J]. Biol Reprod, 2015, 92(1): 7.