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右美托咪定辅助硬膜外麻醉在异位妊娠腹腔镜手术的应用 被引量:10

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摘要 目的观察右美托咪定辅助硬膜外麻醉在异位妊娠腹腔镜手术的应用。方法硬膜外麻醉下行腹腔镜手术的异位妊娠患者60例随机均分为两组:D组气腹开始前10min静脉泵注右美托咪定1μg/kg,术中以0.4μg·kg^(-1)·h^(-1)的速度持续泵注;M组气腹开始前10min静脉泵注0.05mg/kg咪达唑仑,术中以0.05mg·kg^(-1)·h^(-1)的速度持续泵注。记录两组静脉用药前(T0)、气腹开始后15min(T1)、30min(T2)和术毕(T3)时的MAP、HR、脑电双频指数(BIS)和VAS疼痛评分,记录术中不良反应发生情况。结果与M组比较,D组T1~T3时点HR下降(P<0.05),T1、T2时BIS值降低,术中VAS疼痛评分降低(P<0.05),不良反应少。结论右美托咪定复合硬膜外麻醉用于异位妊娠腹腔镜手术时安全、有效。
出处 《江苏医药》 CAS 2017年第11期812-813,共2页 Jiangsu Medical Journal
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