盆炎净胶囊联合抗生素治疗慢性盆腔炎的临床疗效观察

Clinical observation on the treatment of chronic pelvic inflammatory disease with pelvic acid capsule combined with antibiotics

目的 探讨盆炎净胶囊联合抗生素治疗慢性盆腔炎的临床效果.方法 回顾性分析浙江省象山县中医医院2013年10月-2016年10月收治的156例慢性盆腔炎患者的临床资料,随机分为对照组（77例）和观察组（79例）,分别给予常规抗生素治疗和盆炎净胶囊联合抗生素治疗.观察2组治疗后的中医证候积分、治疗有效率、血清炎症因子水平变化情况以及不良反应发生情况,并进行比较.结果 治疗后对2组患者进行中医证候积分评估和比较,存在组间统计学差异,对照组各项指标的评分均显著高于观察组（P〈0.05）.经治疗有效率评估与统计,观察组为93.67%,显著高于对照组的72.73%,经比较差异有统计学意义（P〈0.05）.治疗前2组CRP、TNF-α、IL-6、IL-1β水平经检测和统计差异均无统计学意义;经过不同的治疗之后,2组各项指标组内比较存在统计学差异,均出现明显的下降,且治疗后组间比较也存在统计学差异,观察组均显著低于对照组（P〈0.05）.2组均未出现不良反应.结论 慢性盆腔炎实施常规抗生素治疗联合盆炎净胶囊治疗效果确切,可以更好的改善患者的临床症状,减轻机体的炎性水平,提高治疗效果,是一种安全有效的治疗方案.

Objective To investigate the clinical effect of potting net capsule combined with antibiotics in the treatment of chronic pelvic inflammatory disease.MethodsThe clinical data of 156 patients with chronic pelvic inflammatory disease admitted from October 2013 to October 2016 were retrospectively analyzed.The patients were randomly divided into control group （n=77） and observation group （n=79）.Routine antibiotic therapy and Pelvic acid net capsule combined with antibiotic therapy.The changes of TCM syndromes and treatment efficiency and the level of serum inflammatory factors were observed, and the incidence of adverse reactions was observed and compared.ResultsAfter treatment, the scores of TCM syndromes were evaluated and compared between the two groups.There were significant differences between the two groups.The scores of the control group were significantly higher than those in the observation group （P〈0.05）.The treatment group was 93.67%, which was significantly higher than that of the control group （72.73%）, and the difference was statistically significant （P〈0.05）.There were no significant differences in CRP, TNF-α, IL-6 and IL-1β levels between the two groups before and after treatment.After different treatment, the two groups were compared （P〈0.05）, and there was significant difference between the two groups after treatment.There were statistically significant differences between the two groups after treatment.The observation group was significantly lower than the control group （P〈0.05）.There were no adverse reactions in both groups.ConclusionThe treatment of chronic pelvic inflammatory disease with conventional antibiotic therapy combined with pelvic inflammatory capsule can improve the clinical symptoms, reduce the inflammatory level and improve the therapeutic effect.It is a safe and effective treatment program.