活血化瘀中药丹参辨证治疗冠心病的临床观察

Clinical observation on treatment of coronary heart disease by promoting blood circulation and removing stasis

目的 分析中药丹参辩证治疗冠心病的机制作用.方法 该实验采用动物进行实际探究,即选取大鼠离体心灌流模型、大鼠心肌缺血模型和家兔室性心动过速模型,随后考察不同组别动物在血流动力学指标、冠脉流量、血清超氧化物歧化酶（SOD）含量、血清丙二醛（MDA）含量的对比结果.结果 给药组经过治疗后SOD含量明显增加,MDA含量则明显降低,2组差异具有统计学意义（P〈0.05）.结论 中药丹参在治疗冠心病上作用显著,有利于患者病情的康复,值得在临床上推广应用.

Objective Analyze the mechanism of traditional Chinese medicine Salvia miltiorrhiza in treating coronary heart disease （CHD）.MethodsThe animal experiment using actual research, namely the selection of rat isolated heart perfusion model, rat model of myocardial ischemia and ventricular tachycardia in rabbits model, then the effects of different animal groups in hemodynamics, coronary flow, serum superoxide dismutase （SOD） content, malondialdehyde （MDA） the results of the content.ResultsAfter treatment, the content of SOD was significantly increased and the content of MDA was significantly decreased in the treatment group, and the difference between the two groups was statistically significant （P〈0.05）.ConclusionTraditional chinese medicine Salvia miltiorrhiza has significant effect on the treatment of coronary heart disease, which is beneficial to the recovery of patients＆#39; condition, and is worthy of clinical application.