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罗哌卡因、舒芬太尼单独或联合用药连续蛛网膜下隙阻滞用于分娩镇痛效果的比较 被引量:8

Comparison of the effects of ropivacaine and sufentanil alone or in combination with continuous subarachnoid block for labor analgesia
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摘要 目的 探究罗哌卡因、舒芬太尼单独或联合联合用药连续蛛网膜下隙阻滞用于分娩镇痛效果的比较.方法 本次实验选取了2015年6月-2016年12月在建德市第一人民医院就诊的63例临产自然分娩的产妇,根据产妇入院时间随机进行分组,分为实验组和对照组1、2,各21例.对照组1采用1%罗哌卡因15mg单独治疗;对照组2采用6μg舒芬太尼向产妇治疗;实验组采用1%罗哌卡因15mg、5μg舒芬太尼结合使用治疗.结果 就本次实验结果来看,蛛网膜下隙给药镇痛显效时间即VAS评分≤3分,实验组明显快于对照组1、2(P〈0.05),首次PCEA给药时间即蛛网膜下隙有效镇痛维持时间实验组长于对照组1、2,差异具有统计学意义(P〈0.05).另外,镇痛前即刻VAS评分3组比较差异无统计学意义,镇痛个时间点VAS评分数据3组差异有统计学意义(P〈0.05).另外,3组产妇活跃期、第二产程时间比较差异无统计学意义.结论 相比于单一使用药剂,罗哌卡因、舒芬太尼联合用药连续蛛网膜下隙镇痛用于分娩镇痛对产妇效果更佳对产程影响较小. Objective To investigate the effect of ropivacaine and sufentanil alone or in combination with continuous subarachnoid block for labor analgesia.MethodsIn this experiment, 63 cases of spontaneous delivery of labor in First People's Hospital Jiande City from June 2015 to December 2016 were randomly divided into experimental group and control group according to the time of hospitalization.Each 21 cases.In the control group, 1 mg of ropivacaine was treated with 1 mg of ropivacaine (15 mg) and 5μL of sufentanil.The control group 1 was treated with 1% ropivacaine alone.The control group 2 was treated with 6μl of sufentanil.ResultsIn this experiment, the effect of subarachnoid analgesia was VAS score≤3 points, the experimental group was significantly faster than the control group 1, 2 (P〈0.05), the first PCEA administration time is subarachnoid The effective duration of analgesia in the experimental group was statistically significant (P〈0.05).In addition, VAS score was statistically significant.There was no significant difference between the three groups.In addition, the three groups of maternal active period, the second labor time difference was not statistically significant.ConclusionCompared with the original single use of agents, ropivacaine and sufentanil continuous subarachnoid analgesia for labor analgesia had better effects on maternal effects on labor.
作者 李晓虎 LI Xiao-hu(Department of Anesthesiology, First People's Hospital Jiande City, Jiande 311600, China)
出处 《中国生化药物杂志》 CAS 2017年第6期271-272,275,共3页 Chinese Journal of Biochemical Pharmaceutics
关键词 罗哌卡因 舒芬太尼 连续腰麻 全产程镇痛 产科 自然分娩 ropivacaine sufentanil continuous spinal anesthesia whole labor analgesia obstetrics natural childbirth
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