口服盐酸氨基葡萄糖胶囊配合关节腔内注射玻璃酸钠结合功能锻炼治疗膝骨关节炎的临床研究

Clinical study on treating of the knee osteoarthritis by using glucosamine capsule and injecting sodium hyaluronate combined with appropriate functional exercise

目的 探讨口服盐酸氨基葡萄糖胶囊配合关节腔内注射玻璃酸钠结合功能锻炼的三联疗法治疗膝骨关节炎是否有更加良好的临床效果.方法 选取本院进行治疗的膝骨关节炎患者120例,随机将他们分为2组,研究组进行口服盐酸氨基葡萄糖胶囊联合关节腔内注射玻璃酸钠配合功能锻炼治疗的三联疗法,而对照组只口服盐酸氨基葡萄糖胶囊,分析2组患者的临床效果,确定是否有显著差异.结果 2组患者经过治疗后研究组的VAS评分、血清炎性分子水平及Lequesne指数的研究结果显示,其效果都显著优于对照组（P〈0.05）.结论 口服盐酸氨基葡萄糖胶囊联合关节腔内注射玻璃酸钠配合功能锻炼的三联治疗对膝骨关节炎效果显著,在提高患者生活质量方面更加有利.

Objective To investigate the clinical effect of three capsule combined with Function injection combined with functional exercise in the treatment of knee osteoarthritis.Methods120 patients with knee osteoarthritis were randomly divided into two groups, the study group took orally hydrochloride capsule combined with joints injection combined with functional exercise therapy, and the control group only oral glucose capsules.two groups of patients after a period of treatment.ResultsIn the VAS score, lequesne index and serum inflammatory molecular level of the two groups were significantly better than the control group （P〈0.05）.ConclusionWhich the clinical study on treating of the knee osteoarthritis by using glucosamine capsule and injecting sodium hyaluronate combined with appropriate functional exercise has a significant effect on knee osteoarthritis, and more favorable in improving the quality of life of patients.