经皮椎体成形术治疗疼痛性骨质疏松性胸腰椎压缩性骨折的疗效及其止痛机制

Therapeutic effect and analgesic mechanism of percutaneous vertebral angioplasty in the treatment of painful osteoporotic thoracolumbar vertebral compression fracture

目的 探讨经皮椎体成形术治疗疼痛性骨质疏松性胸腰椎压缩性骨折的疗效及其止痛机制.方法 选取浙江省绍兴第二医院2014年5月-2016年5月收治的疼痛性骨质疏松性胸腰椎压缩性骨折患者80例,随机将这些患者分为经皮椎体成形术组（40例）和保守治疗组（40例）2组,对2组患者的临床疗效、VAS评分和ODI评分进行统计分析.结果 经皮椎体成形术组患者治疗的总有效率95.0%（38/40）,显著高于保守治疗组75.0%（30/40）（P〈0.05）;2组患者治疗后的VAS评分和ODI评分均显著低于治疗前（P〈0.05）;治疗前2组患者的VAS评分、ODI评分之间的差异无统计学意义,治疗后经皮椎体成形术组患者的VAS评分、ODI评分均显著低于保守治疗组（P〈0.05）.结论 经皮椎体成形术治疗疼痛性骨质疏松性胸腰椎压缩性骨折的疗效较保守治疗显著,具有更好的止痛效果.

Objective To investigate the therapeutic effect and analgesic mechanism of percutaneous vertebral angioplasty in the treatment of painful osteoporotic thoracolumbar vertebral compression fracture.Methods80 cases of patients with painful osteoporotic thoracolumbar vertebral compression fracture in Shaoxing second hospital from May 2014 to May 2016 were selected, they were randomly divided into percutaneous vertebroplasty group （40 cases） and conservative treatment group （40 cases） two groups, the clinical efficacy, VAS scores and ODI scores of the two groups were statistically analyzed.ResultsThe total treatment effective rate of the percutaneous vertebroplasty group 95% （38/40） was significantly higher than the conservative treatment group （30/40） （P〈0.05）;The VAS scores and ODI scores of the two groups after treatment were significantly lower than before treatment （P〈0.05）;The differences of VAS scores and ODI scores before treatment between the two groups were not significant.The VAS score and ODI score after treatment of the percutaneous vertebroplasty group were significantly lower than the conservative treatment group （P〈0.05）.ConclusionThe therapeutic effect of percutaneous vertebral angioplasty in the treatment of painful osteoporotic thoracolumbar vertebral compression fractures is more significant than conservative treatment, it has better analgesic effect, so is worthy of promotion in the clinical.