期刊文献+

奥美拉唑联合伊托必利治疗食管炎的疗效分析 被引量:2

原文传递
导出
摘要 目的观察反流性食管炎应用奥美拉唑联合伊托必利治疗的临床疗效。方法选择2015年1月-2016年6月滨海新区汉沽中医医院消化科住院收治110例反流性食管炎患者为研究对象,以随机数字表法分组,分为对照组和观察组,每组各55例。对照组服用促胃动力药物伊托必利与抑胃酸药物法莫替丁治疗,观察组给予伊托必利联合质子泵抑制剂奥美拉唑治疗,观察两组服药后的治疗效果并进行生存质量评分。结果观察组治疗总有效率为94.55%,明显高于对照组的78.18%,差异有统计学意义(P<0.05),观察组治疗后生存质量评分明显高于对照组,差异有统计学意义(P<0.05)。结论对反流性食管炎采用奥美拉唑联合伊托必利治疗能够有效缓解患者的临床症状,提高治疗效果,降低不良反应发生率,值得临床推广应用。
作者 梁艳苓
出处 《中国城乡企业卫生》 2017年第6期110-112,共3页 Chinese Journal of Urban and Rural Enterprise Hygiene
  • 相关文献

参考文献5

二级参考文献58

  • 1中华消化内镜学会.反流性食管病/反流性食管炎诊断及治疗方案(试行).胃肠病学,2000,5(4):251-251.
  • 2Weijenborg PW, Cremonini F,Smout AJPM, et al.PPI ther- apy is equally effective in well-defined non-erosive reflux disease and in reflux esophagitis: A meta-analysis[ J ] .Neurogastroenterology and Motility,2012,24(8) :747-750.
  • 3Vakil N, van Zanten SV, Kahrilas P, et al. The Montrealdefinition and classification of gastroesophageal reflux disease: a global evidence-based eonsensus[J]. Am J Gastroenterol, 2006,101 (8) : 1900-1920.
  • 4Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease[J]. Am J Gastroenterol, 2013,108(3) :308-329.
  • 5E1-Serag HB, Sweet S, Winchester CC,et al. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review[J]. Gut, 2014,63(6) : 871-880.
  • 6Lundell LR, Dent J, Bennett JR, et al. Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification[J]. Gut, 1999, 45(2) : 172-180.
  • 7ParfittJR, Gregor JC, Suskin NG, et al. Eosinophilic esophagitis in adults : distinguishing features from gastroesoghageal reflux disease.- a study of 41 patients [J]. Mod Pathol, 2006,19(1) :90-96.
  • 8Jones R, Junghard O, Dent J, et al. Development of the GerdQ, a tool for the diagnosis and management of gastro- oesophageal reflux disease in primary care E J~. Aliment Pharmacol Ther, 2009,30(10) : 1030-1038.
  • 9Cui R, Zhou L, Lin S, et al. The feasibility of light microscopic measurements of intercellular spaces in squamous epithelium i.n the lower-esophagus of GERD patients[J]. Dis Esophagus,2011,24(1) : 1-5.
  • 10Jamieson JR, Stein HJ, DeMeester TR, et al. Ambulatory 24-h esophageal pH monitoring: normal values, optimal thresholds, specificity, sensitivity, and reproducibility [J]. Am J Gastroenterol, 1992, 87(9) :1102 1111.

共引文献75

同被引文献12

引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部