氯胺酮为麻醉MECT治疗的不良反应临床观察

Clinical observation on adverse reaction of ketamine in anesthesia MECT

目的观察MECT治疗麻醉中应用氯胺酮对不良反应的影响。方法选择本院2014年6月~2016年6月收治的行MECT治疗的患者102例,随机抽取50例作为观察组,治疗中应用氯胺酮麻醉,剩余52例作为对照组,给予丙泊酚麻醉,观察两组患者呼吸恢复时间、意识恢复时间、定向力恢复时间、抽搐能量指数、不良反应发生情况。结果两组患者呼吸恢复时间、意识恢复时间、定向力恢复时间无差异,不存在统计学意义(P>0.05);观察组抽搐能量指数、不良反应发生率低于对照组,差异具有统计学意义(P<0.05)。结论 MECT治疗中,麻醉药物选择为氯胺酮时,麻醉效果与丙泊酚相近,但不良反应较少,具有更高的安全性。

Objective To observe the effect of ketamine on adverse reaction in MECT treatment. Methods 102 cases of MECT treated in our hospital from June 2014 to June 2016 were selected,,50 cases were randomly selected as the observation group,ketamine anesthesia was used in the treatment,and the remaining 52 cases as the control group,the respiratory recovery time,the recovery time of consciousness,the recovery time of directional force,the energy index and the incidence of adverse reactions were observed in the two groups. Results Two groups of patients with respiratory recovery time,recovery time,recovery time of orientation differences,there was no statistical significance（ P〈0. 05）; the observation group seizure energy index and the incidence of adverse reaction was lower than the control group,the difference was statistically significant（ P〈0. 05）. Conclusion In the treatment of MECT,the anesthetic effect of ketamine is similar to that of propofol,but it has less adverse reactions and higher safety.