早期应用脂肪基质血管成分技术对糖尿病足患者溃疡的治疗效果观察

Observation of the Therapeutic Effect of Early Application of Stromal Vascular Fraction Technology on Diabetic Foot Ulcer

目的探讨早期应用脂肪基质血管成分(stromal vascular fraction,SVF)技术对糖尿病足患者溃疡的治疗效果。方法2015年5月至2016年12月,便利抽样法选取在南京大学医学院附属鼓楼医院伤口护理室治疗的糖尿病足患者66例为研究对象。按数字随机表法将其分为观察组(n=35)和对照组(n=31)。观察组患者采用SVF技术治疗后常规换药,而对照组患者采用常规换药方法。观察两组患者的创面愈合时间、治疗总显效率及不良反应情况。结果观察组和对照组患者伤口平均愈合时间分别为(33.4±8.6)d和(41.8±5.9)d,差异有统计学意义(P<0.001)。观察组患者治疗的总显效率为85.72%,高于对照组的64.52%,差异有统计学意义(P<0.05)。两组患者均无不良反应。结论 SVF技术用于治疗糖尿病足溃疡患者疗效显著,无不良反应,促进了创面的愈合。

Objective To observe the therapeutic effect of SVF （stromal vascular fraction） technology on diabetic foot ulcer.Methods By convenience sampling, 66 cases were selected and randomly divided into observation group （n=35） and control group （n=31）. The observation group was applied with SVF technology and then treated with conventional dressing changes, and control group was treated with conventional dressing only. The wound healing time, healing rate and systemic reactions were assessed.Results The data indicated that the average healing time in treatment group and control group was （33.4±8.6） days and （41.8±5.9） days, respectively （P〈0.001）. The total efficiencyin observation group （85.72%） was higher than that of control group （64. 52%） （P 〈 0.05）. The adverse effects were not observed in two groups.Conclusion The SVF technique has obvious curative effect on diabetic foot with no side effects. It is helpful to relieve the pain in patients with diabetic foot and to promote the healing of wound.