癫痫患儿发病的危险因素的分析

The hazards analysis of epilepsy children morbidity

目的探讨癫痫患儿发病的危险因素。方法选取2013年1月~2015年1月我院120例癫痫患儿作为癫痫组,选取同期健康体检者100例作为对照组。比较两组研究对象一般特征、癫痫家族史、出生状况、既往病史等,采用多因素非条件Logistic回归观察癫痫的危险因素。结果癫痫组患儿发病年龄0~1岁者占比高于对照组,>5~6岁者占比低于对照组(P<0.05);癫痫家族史、母亲适龄怀孕、产伤、高热惊厥、颅脑感染、颅脑损伤患者发生癫痫的比例较高,差异均有统计学意义(P<0.05);多因素非条件Logistic回归分析结果显示,产伤、母亲适龄怀孕、高热惊厥史、颅脑损伤史、癫痫家族史是癫痫发作的危险因素(P<0.05)。结论分析癫痫患儿发病的危险因素,产伤、母亲适龄怀孕、高热惊厥史、颅脑损伤史、癫痫家族史是癫痫发作的危险因素,可以为指导临床治疗癫痫提供可靠的理论依据。

Objective To approach hazards of epilepsy children morbidity.Methods The 120 children with epilepsy in our hospital from January 2013 to January 2015 were selected as epilepsy group,then 100 healthy children check-up in our hospital in the same period were selected as control group.The general features,epilepsy family history,born,anamnesis and epilepsy were compared between the two groups.The multiple-factor non-conditional Logistic regression analysis was used to analyzed the epilepsy hazards.Results The proportion of children whose epilepsy onset at 0-1 age in the epilepsy group was higher than the control group,proportion of children whose epilepsy onset at〉 5-6 age was lower than the control group（P〈0.05）;the proportion of epileptic seizure in children with epilepsy family history,mother age pregnancy,birth injury,hyperpyretic convulsion,brain infection,craniocerebral injury was higher,the differences were statistical significance（P〈0.05）.The multiple-factor non-conditional Logistic regression analysis showed that,birth injury,mother age pregnancy,hyperpyretic convulsion,craniocerebral injury,epilepsy family history were hazards of epileptic seizure（P〈0.05）.Conclusion Analyzing of the risk factors of the epilepsy,the birth injury,mother age pregnancy,hyperpyretic convulsion,craniocerebral injury,epilepsy family history are hazards of epileptic seizure,which can guide clinical treatment epilepsy for providing reliable theory basis.