超声诊断对神经系统发育异常胎儿的宫内转归及预后分析

Intrauterine outcome and prognosis analysis of fetuses with abnormal neurodevelopment by ultrasound diagnosis

目的探讨神经系统发育存在异常的胎儿行以超声诊断措施对其宫内转归情况及预后情况的作用。方法综合本院的就诊情况,随机选择2015年1月~2017年1月期间在我院接受诊治的经超声确诊侧脑宽度在(9.00±0.80)mm的胎儿68例,将其作为A组,并于同期择取68例神经功能异常的胎儿作为B组。分析两组胎儿在超声诊断设备下的结果和相关资料并予以全面的分析和总结。结果在A组中,1例胎儿确诊进展成重度的扩张变化,5例进展为轻度的扩张变化,两组胎儿宫内转归情况的差异有统计学意义(P<0.05);另外,胎儿的侧室宽度进展情况和预后存在较为显著的联系。结论在影像学临床当中,侧脑宽度在(9.00±0.80)mm左右的胎儿很可能会发生宫内进展情况,针对这种情况必须予以定期诊察,如果存在透明隔腔消失或者是脉络丛囊肿症状,有条件者需要接受MRI深入检查确诊;此外,针对宫内进展情况及颅脑急性进展较显著的胎儿,需要尽快诊断和干预,以保证胎儿的健康。

Objective To explore the effect of ultrasound diagnostic measures on the intrauterine outcome and the prognosis of the fetuses with abnormal nervous system development. Methods Based on the treatment situation in our hospital, a total of 68 fetuses with lateral brain ventricle width（9.00 ±0.80） mm diagnosed and treated in our hospital from January 2015 to January 2017 were randomly chosen as group A. And 68 fetuses with neurological abnormalities in the same period were chosen as group B. The results and the relevant information of the two groups in the ultrasound diagnostic equipment were comprehensively analyzed and summarized. Results In the group A, 1 fetus was diagnosed with progression to severe dilatation change, 5 cases progressed to mild dilatation. There was a statistically significant difference in intrauterine outcome between the two groups（P〈0.05）. In addition,there was a significant correlation between the progress of the lateral ventricle width and the prognosis in fetuses. Conclusion In the clinical imaging, the fetuses with lateral brain ventricle width（9.00±0.80） mm are likely to develop intrauterine progress. For this situation, it is necessary to check regularly. If there is a transparent compartment disappear or choroid plexus cyst symptom, then the fetus conditionally need to accept MRI in-depth examination for confirmation. In addition, for fetus with significant intrauterine progress and acute brain progress, diagnosis and intervention as soon as possible are needed to ensure the health of the fetus.