补肾活血除湿法治疗免疫性不孕不育患者的临床疗效观察

Observation on clinical effect of Bushenhuoxuechushi method in the treatment of immune infertility patients

目的观察补肾活血除湿法治疗免疫性不孕不育患者的临床疗效。方法选取2015年1月~2016年1月我院收治的免疫性不孕不育患者80例,根据治疗方式的不同分为观察组(40例,给予补肾活血除湿法治疗)、对照组(40例,给予西药治疗)。观察两组患者的临床总有效率、不良反应发生率、阳性抗体转阴情况。治疗前后,检测内分泌指标(促卵泡生成素、雌二醇)水平。结果观察组临床总有效率为97.50%、总不良反应发生率为2.50%、阳性抗体总转阴率为97.50%,均优于对照组患者的临床总有效率62.50%、总不良反应发生率15.00%、阳性抗体总转阴率85.00%(P<0.05)。治疗后,两组促卵泡生成素均显著下降,雌二醇显著上升,且组间比较存在显著差异(P<0.05)。结论免疫性不孕不育患者应用补肾活血除湿法治疗疗效显著,可有效改善性激素指标,提高受孕率,临床上值得推广。

Objective To observe the clinical effect of Bushenhuoxuechushi method in the treatment of immune infertility patients. Methods 80 patients with immunodeficient infertility in our hospital from January 2015 to December2016 were selected. According to the different treatment methods, the patients were divided into observation group（n=40）treated with Bushenhuoxuechushi method and control group（ n = 40） given Western medicine treatment. The clinical total effective rate, the incidence of adverse reactions and turning antibody from positive to negative were observed in the two groups of immunological infertility patients. The levels of endocrine indicators（follicle stimulating hormone,estradiol） were detected before and after treatment. Results The total effective rate 97.50%, the total adverse reactions rate 2.50%, the total rate of turning antibody from positive to negative 97.50% in the observation group were superior to the total effective rate 62.50%, the total adverse reaction rate 15.00%, the total rate of turning antibody from positive to negative 85.00% in the control group（P〈0.05）. After treatment, the follicle-stimulating hormone in the two groups decreased significantly, the estradiol increased significantly. And there was significant difference between the two groups（P〈0.05）. Conclusion The application of Bushenhuoxuechushi method in treatment of patients with immune infertility is significantly effective, which can improve the sex hormone indexes, improve the pregnancy rate, and is worthy of promotion in clinical.