摘要
目的通过对22例蕈样肉芽肿(mycosis fungoides,MF)住院患者临床资料进行分析,为早期诊断和治疗提供帮助。方法选取2007年-2013年中国医科大学第一医院皮肤科22例MF住院患者临床资料进行回顾性分析。结果顽固性瘙痒、皮疹泛发、治疗不佳、外周血检查相关指标异常升高是早期MF的重要线索。早期病变,局部应用糖皮质激素联合NB-UVB、干扰素治疗,可长期缓解。结论临床上应对淋巴结肿大患者进行病理活检,免疫组化检查对MF分型很重要。MF病程缓慢,恶性度较低,在出现典型的肿瘤期表现前早期诊断治疗,大部分患者预后较好。
Objective Analyzed 22 cases mycosis fungoides the clinical characteristics to provide help for the early diagnosis and treatment.Methods The clinical data of 22 cases in the department of No. 1 hospital of Chi-na medical university from 2007 to 2013 were retrospectively analyzed.Results Intractable pruritus,generalized rash,resistant to routine treatment,abnormal increase of the peripheral blood test indexes are important clues for early MF. Topical corticosteroids in combination with NB-UVB,interferon treatment can get a stable status for a long time for early lesions.Conclusion Biopsy and immunohistochemistry are important for improving the diagnosis efficiency. The course of the disease is chronic and progress slowly,good prognosis can be obtained for most early patients with proper treatment.
出处
《中国医学文摘（皮肤科学）》
2017年第3期339-342,共4页
China Medical Abstracts(Dermatology)
基金
辽宁省高等学校优秀人才支持计划(LJQ2014088)
关键词
蕈样肉芽肿
诊断
治疗
预后
Mycosis fungoides
Diagnosis
Treatment
Prognosis
