糖尿病患者急性心肌梗死发生与ABO血型的相关性分析

Analysis of correlation between acute myocardial infarction with ABO blood type in patients with diabetes

目的 研究糖尿病患者急性心肌梗死发生与ABO血型抗原分布的关系.方法 选择糖尿病患者2 052例,所有患者有血型记录.根据血型分为A型组（n=625）、B型组（n=548）、AB型组（n=204）、O型组（n=675）.比较各组急性心肌梗死发生概率.结果 （1）A型组急性心肌梗死发生概率为9.44%,B型组为8.03%,AB型组为6.86%,O型组为5.19%,各组急性心肌梗死发生概率差异有统计学意义（χ2=9.02,P〈0.05）.（2）糖尿病患者急性心肌梗死发生率A型组为9.44%,明显高于非A型组的6.52%,差异有统计学意义（χ2=5.41,P〈0.05）.（3）糖尿病患者急性心肌梗死发生率非O型组为8.50%,明显高于O型组的5.19%,差异有统计学意义（χ2=7.24,P〈0.05）.结论 糖尿病患者急性心肌梗死发生与ABO血型抗原分布存在相关性,A型血糖尿病患者比非A型血糖尿病患者更容易发生急性心肌梗死,非O型血糖尿病患者比O型血糖尿病患者更容易发生急性心肌梗死.

Objective To study the relationship between acute myocardial infarction with the distribution of ABO blood type antigen in patients with diabetes.Methods 2 052 patients with diabetes were selected.All patients had blood type records.The patients were divided into A blood type group（n=625）,B blood type group（n=548）,AB blood type group（n=204）,O blood type group（n=675）.Records were analyzed for the incidence of acute myocardial infarction.Results （1）The incidence rate of acute myocardial infarction in the A blood type group was 9.44%,which in the B blood type group was 8.03%,whith in the AB blood type group was 6.86%,which in the O blood type group was 5.19%,there was significant difference among the four groups（χ2=9.02,P〈0.05）.（2）For patients with diabetes,the incidence rate of acute myocardial infarction in the A blood type group was 9.44%,which was significantly higher than 6.52% in the non-A blood type group,the difference was statistically significant（χ2=5.41,P〈0.05）.（3）For patients with diabetes,the incidence rate of acute myocardial infarction in the non-O blood type group was 8.50%,which was significantly higher than 5.19% in the O blood type group,the difference was statistically significant（χ2=7.24,P〈0.05）.Conclusion There is a correlation between acute myocardial infarction with ABO blood type in patients with diabetes.For patients with diabetes,the patients with A blood type develop acute myocardial infarction more often than patients with non-A blood type,patients with blood type non-O develop acute myocardial infarction more often than patients with blood type O.