血浆脑钠肽及脂蛋白a水平与急性冠脉综合征患者冠脉病变程度相关性研究被引量：5

Correlation between serum level of BNP,lipoprotein a and severity of coronary lesions in patients with acute coronary syndrome

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摘要冠心病是多重因素共同作用的结果.近年来,脂蛋白a[Lp（a）]与N-末端脑钠肽前体（NT-proBNP）在冠心病及冠状动脉病变程度中的作用越来越受到关注.研究表明,LP（a）是冠心病的独立危险因素,且可作为冠状动脉病变严重性的判定指标之一,但不同的研究结果存在争议;NT-proBNP是脑钠肽前体（pro-BNP）裂解成脑钠肽（BNP）时的产物,血浆浓度比较高,且不受心功能的影响,心肌缺血时亦能明显升高,可用于冠心病患者严重程度的评估.因此,研究拟通过前瞻性研究,结合冠状动脉造影结果,探讨Lp（a）与NT-proBNP在冠心病及冠状动脉病变进程中的作用.

作者谭星李建国 Tan Xing Li Jianguo(Department of Cardiovascular Medicine, Fenyang Hospital Affiliated to Shanxi Medical University, Fenyang, Shanxi 032200, Chin)

机构地区山西医科大学附属汾阳医院心血管内科

出处《中国基层医药》 CAS 2017年第13期2072-2074,共3页 Chinese Journal of Primary Medicine and Pharmacy

关键词急性冠脉综合征脑钠肽脂蛋白A

分类号 R541.4 [医药卫生—心血管疾病]

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