电针治疗心血瘀阻型冠心病心绞痛的临床观察

Clinical Observation on Eletro-acupuncture in Treatment of Angina Pectoris of Coronary Heart Disease with Blood Stasis Syndrome

目的观察电针治疗心血瘀阻型冠心病心绞痛的临床疗效。方法 90例患者随机分为电针组和对照组各45例,对照组予以辛伐他汀片、阿司匹林肠溶片和丹参川芎嗪治疗,有高血压、糖尿病者予以降压、降糖治疗;电针组在对照组治疗基础上加用电针治疗。两组10d为1疗程,1个疗程结束后观察各组临床症状疗效、心电图疗效、治疗期间药物副反应发生情况和预后心绞痛复发情况。结果电针组临床症状疗效总有效率显著高于对照组,两组间比较具有显著统计学意义(P<0.05);电针组心电图疗效总有效率极显著高于对照组,两组间比较具有极显著统计学意义(P<0.01);电针组的药物副反应发生率极显著低于对照组,两组间比较具有极显著统计学意义(P<0.01);电针组治疗结束后2周和4周的复发率分别低于对照组的20.0%和66.7%,2周后两组间比较具有显著统计学意义(P<0.05),4周后两组间比较具有极显著统计学意义(P<0.01)。结论电针疗法安全有效,与西药联用不仅能提高临床疗效,还能减轻西药引起的副作用和减少复发率,同时还能良性调节心电图的异常改变。

Objective To observe the effect of eletro-acupuncture（ EA） in treatment of angina pectoris of coronary heart disease with blood stasis syndrome. Methods 90 cases of patients with angina pectoris of coronary heart disease with blood stasis syndrome were divided into EA group and control group,45 cases in each group. Control group was treated with simvastatin tablets,aspirin-enteric-coated tablets and salvia ligustrazine,patients with hypertension or diabetes received related tablets; EA group added EA on the basis of control group. Time of therapy were 10 d in both groups. The effect of clinical symptoms and ECG,the adverse events,and the recurrence rate were observed at the end of treatment. Results The total effective rate of EA group was 93. 3%,which was higher than 77. 8% of control group with significant difference（ P〈0. 05）; the total ECG effective rate of EA group was 100%,which was significantly higher than 51. 1% of control group with a very significant statistical significance（ P〈0. 01）; the incidence rate of adverse events was 0. 0% in EA group,which was significantly lower than 57. 8% of control group（ P〈0. 01）. The recurrence rate of EA group at the 2ndand the 4^（th）week after treatment were 0. 0% and 6. 7% respectively,higher than 20.0% and 66. 7% of control group,there was a significant difference between the two groups at the 2^nd week and a statistically significant difference between the two groups at the 4thweek. Conclusion EA therapy is safe and effective in improving the clinical efficacy and reducing the side effects caused by western medicine,which can also adjust the abnormal changes of ECG.