酸枣仁汤的神经药理作用及分子机制研究进展

Research Progress of Nerve Pharmacological Effects and Molecular Mechanism of Suanzaoren Decoction

酸枣仁汤为养血安神经典古方,具有镇静催眠、抗抑郁、抗焦虑等多种作用于中枢神经系统的药理活性。对近几年酸枣仁汤的镇静催眠、脑保护、改善学习记忆、改善睡眠时相结构、抗抑郁等神经药理作用及分子机制研究成果进行综述,以期为酸枣仁汤的临床应用及进一步研究提供参考。

Suanzaoren decoction is a classic ancient prescription for nourishing the blood and tranquilization with pharmacological activities of sedative-hypnotic,anti-depressants,anti-anxiety and other effects in the central nervous system. Reported in this paper,the nerve pharmacological effects and molecular mechanism research results of Suanzaoren decoction in recent years,such as sedative-hypnotic,brain protection,improving the learning and memory,improving sleep phase structure and anti-depressant effect were reviewed,hoping to provide a reference for clinical application and further research of Suanzaoren decoction.