正常孕妇及不同程度妊娠期高血压疾病患者血清皮质醇水平的差异性研究

Clinical Study of the Effect of the Serum Cortisol Level of Normal Pregnant Women and Pregnancy Induced Hypertension Syndrome Patients

目的测定正常孕妇及不同程度妊娠期高血压病患者体内的血清皮质醇水平,对其差异性进行探讨分析。方法将我院93例不同程度妊娠期高血压病患者作为观察组,对照组为40例正常孕妇。采用化学发光法检测正常孕妇及妊娠高血压病人体内血清皮质醇浓度。结果观察组血清皮质醇水平明显较正常对照组高,且随着病情严重程度的增加,血清皮质醇水平明显增加,组间血清皮质醇水平值均有显著性,具有统计学意义(P<0.05)。结论对孕妇血清皮质醇水平的测定,有利于妊娠高血压征的早期发现治疗及病情分期的判断提供指导,在临床中具有广泛的应用价值,值得进一步推广。

Objective The levels of serum cortisol in normal pregnant women and patients with essential hypertension pregnancy were measured,to explore analyzed differences. Methods 93 cases of patients with different degrees of pregnancy-induced hypertension in our hospital as the observation group, the control group of 40 cases normal pregnant women. Detected serum cortisol concentration in normal pregnant women and pregnancy-induced hypertension patient by chemiluminescence method. Results The serum cortisol level of observation group was significantly higher than that of normal control group ,and increased with the severity of the disease, the serum cortiso] levels were significantly increased, the value of serum cortisol levels between the two groups was significant, statistically significant （P〈0.05）. Conclusion The determination of serum cortisol levels in pregnant women, conducive to the early detection of pregnancy induced hypertension and provide guidance for the judgment of the disease stage, and has a wide range of application value in clinical practice.