深圳地区500例过敏性皮肤病斑贴试验结果分析

Patch Test Results of 500 Cases with Allergic Diseases in Shenzhen Area

目的分析深圳地区过敏性皮肤病患者常见的接触性过敏原。方法对来自我科门诊的500例过敏性皮肤病患者进行瑞敏欧洲标准系列斑贴试验,对结果进行统计学分析。结果 500例患者中,斑贴试验总阳性率为49.80%,阳性率列前5位的过敏原依次为硫酸镍(21.20%)、卡松CG(14.40%)、氯化钴(7.40%)、重铬酸钾(5.80%)、甲醛(4.80%),男女斑贴试验阳性率差异无统计学意义,各病种间斑贴试验总阳性率差异有统计学意义。结论硫酸镍是过敏性皮肤病患者最常见的接触性过敏原。

Objective In order to analyze the contact allergens of patients with allergic skin diseases in Shenzhen area. Methods Patch test of European standard series allergens was performed on 500 patients with allergic diseases. Results The total positive rate of 500 patients＇ patch test with European standard series was 49.80%. The top-five common antigens were nickel sulfate （ 21.20% ）, kathan CG （ 14.40% ）, cobalt chloride （ 7.40% ）, potassium dichromate （ 5.80% ） and formaldehyde （4.80%）. There was no significant difference in the positive rate of patch test in different sex. There was a significant difference in the total positive rate of patch test among different types of diseases. Conclusion Nickel sulfate was the most common contact allergen inducing the allergic skin diseases.